Search results for protein

“Woodrum, M.D., a U-M resident in general surgery, will present new research results showing that smooth muscle cells from aortas of male rats contain 2.5 times more destructive MMP-9 protein and 10 times the level of MMP-9 gene expression compared to the same cells from female rat aortas.”

“A key driver of circadian rhythms is melatonin. Often called the sleepiness hormone, melatonin is a protein produced primarily in the pineal gland of the brain. Its levels oscillate daily, peaking one hour into sleep and ebbing two hours after waking.”

“Researchers depleted the Foxp3-expressing cells in mice and assessed the animals' behavior. They found that Foxp3 depletion caused temporary anxiety and depression-like behaviors due to the activation of inflammasomes, multi-protein complexes that drive the body's inflammatory response.”

“A recent study found that a nasal spray that delivered neural stem cell extracellular vesicles—tiny particles that carry proteins and genetic material—reduced inflammation and improved brain function in a mouse model of Alzheimer’s disease, offering a safer, less risky approach.”

“Cytokines are a broad category of naturally occurring small proteins that are important in cell signaling. They are released by cells and influence the behavior of other cells. Designer cytokines are genetically engineered proteins that perform specific functions.”

“AGEs can crosslink with protein and lipids, including collagen, reduce the elasticity of our heart and contribute to a stiffening of blood vessels, and promote high blood pressure, putting us at risk for cardiovascular disease.”

“It uses a modified version of the chimpanzee adenovirus (ChAdOx1) to deliver the genetic information that codes for the SARS CoV-2 spike protein. Adenovirus vector vaccines are currently being tested for numerous infectious agents, ranging from malaria to HIV.”

“In that same experiment, semaglutide produced more favorable changes in spatial memory, exploratory behavior, and blood glucose control than the calorie-restricted diet. One possible link between eating less and aging better is the work cells do to maintain their proteins.”

“A recent study found that a ketogenic diet boosted levels of brain-derived neurotrophic factor (BDNF)—a key protein that supports brain health—by 47%, highlighting the diet's potential to support brain health even in people without cognitive impairment.”

“They don’t yet know which receptors irisin interacts with, but they suggest it prompts the production of proteins that in turn increase the expression of key genes—those that drive immature cells to differentiate into osteoblasts, which synthesize new bone.”