Search results for aging

“A meta-analysis of over 30 studies conducted in China finds that people 50 years old and older are around 2.5x more likely to progress to a severe case of COVID-19, males had 1.3x higher risk, smoking increased risk 1-2x, and pre-existing conditions such as hypertension, diabetes, and cardiovascular disease increased risk by 2-3x.”

“In 1,334 dementia-free adults with a mean age of 84, levels below 25 nanomoles per liter were associated with a 91 percent higher rate of all-cause dementia and a 128 percent higher rate of Alzheimer's dementia over seven years.”

“Epigenetic alterations don't change the DNA sequence but how it is 'read.' In particular, DNA methylation, the addition of a methyl group (or molecule), is an epigenetic switch that can stably turn off genes, suggesting the potential to cause cancer just as a genetic mutation can.”

“A recent meta-analysis also found small benefits in selected cognitive domains, including memory and processing speed, with responses that may depend on age, diet, baseline stores, stress, dose, and the cognitive test used.”

“We need inflammation. Without it, we are vulnerable. However, when inflammation is chronic, it can be damaging and goes from being adaptive to playing a role in driving the diseases that largely constitutes what we call aging.”

“In a two-year trial of 237 postmenopausal women, approximately 9 to 10 grams per day combined with resistance training and walking did not add a bone-density benefit, so its role is better framed around muscle and physical function.”

“Aging leads to progressive muscle loss (sarcopenia), decreased strength, and functional decline, significantly affecting quality of life. Creatine supplementation, particularly combined with resistance training, has emerged as a valuable nutritional strategy to mitigate these negative consequences of aging.”

“Vigorous Exercise and Brain Aging Lactate—produced at high levels during vigorous exercise—mediates some of the benefits of exercise on learning and memory through its effects on BDNF expression in neurons.”