Search results for small vessel disease

“Preventing dementia requires a lifelong and multipronged approach that involves keeping inflammation (and its aging effects) at bay and making healthy lifestyle choices, such as exercising and consuming omega-3 fatty acids.”

“Vascular dysfunction is a common feature of most forms of dementia, including Alzheimer's disease. Identifying and treating vascular problems in the brain's smallest blood vessels could postpone the onset of symptoms and improve the quality of life for people with dementia.”

“Vascular dysfunction, the loss of normal endothelial tone and permeability of blood vessels, is a common feature of most forms of dementia, including Alzheimer's disease. People who carry the APOE4 gene are at greater risk for vascular dysfunction and Alzheimer's disease.”

“Elevated homocysteine levels often slip under the radar during routine checkups, yet they quietly raise our risk for heart disease, stroke, high blood pressure, Alzheimer's, and even shorten our lifespan.”

“When ingested by humans, resveratrol binds to sirtuins, altering their affinity for NAD+ and their protein substrates, thereby increasing sirtuins' activity. As such, resveratrol presents a promising therapeutic strategy to ameliorate age-related diseases and extend healthspan.”

“In rodents, leucine is necessary and sufficient to activate mTOR and drive the development of atherosclerosis — a disease characterized by the hardening and narrowing of blood vessels. The effects of leucine on mTOR and atherogenesis occur only at a per-meal protein dose of 25 grams or more.”

Dr. Rhonda Patrick covers lithium microdosing, reducing homocysteine, aluminum's link to cancer, and beta-alanine and alpha-lipoic acid supplements.

“Apolipoprotein B, or ApoB for short, is a protein involved in lipid metabolism and is a robust predictor of cardiovascular disease risk. Healthy lifestyle behaviors, such as following a Mediterranean diet, exercising, and taking supplements like zinc and omega-3 fatty acids, may reduce ApoB levels.”

“Studies in animals show that if Mfsd2a is defective or missing (which can happen with age or genetics), DHA levels in the brain decrease by more than 50%, potentially compromising the blood-brain barrier.”

“Selected nutrients may help some people as part of a broader prevention plan. In small placebo-controlled trials, 400 milligrams of riboflavin daily and 100 milligrams of coenzyme Q10 three times daily each reduced migraine frequency or responder outcomes.”