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PremiumThe thymus is a lymphoid organ behind the sternum that produces and matures T cells, central immune cells involved in responses to pathogens, allergies, and autoimmunity. Its age-related shrinkage—thymic involution—reduces T-cell immunity and production, although long-term…
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Based on available source text from 9 of the first 10 results.
Thymic involution
“Role of T cells in cancer, autoimmunity, and fighting infection The thymus is a lymphoid organ located behind the sternum and near the heart. Its primary purpose is to produce mature T cells, a type of white blood cell involved in allergies, autoimmunity, and immunity against pathogens.”
In world's first: whole, functional thymus grown in live mice and able to produce T cells
“FTA: >Patients who need a bone marrow transplant and children who are born without a functioning thymus could all benefit. >Ways of boosting the thymus could also help elderly people. The organ shrinks with age and leads to a weaker immune system.”
Brain-derived neurotrophic factor (BDNF)
“The primary site of BDNF production is the brain, but other tissues also produce it, including the heart, lungs, kidneys, liver, prostate, intestinal epithelium, skeletal muscle, spleen, and thymus.”
Long-term distance cycling reduces hallmarks of aging: thymic involution - "cyclists' thymuses were making as many T cells as those of a young person"
“> An organ called the thymus, which makes immune cells called T cells, starts to shrink from the age of 20 and makes less T cells. In this study, however, the cyclists' thymuses were making as many T cells as those of a young person. View full publication 1.”
Thymic Involution
Thymic involution is age-related shrinkage of the thymus and reduction in T cell immunity.
Vitamin C
“Animal muscle meat is, for the most part, a very poor source of vitamin C. Organ meats such as cooked beef spleen, lung, and thymus contain moderate amounts (50 milligrams or less per serving) of vitamin C, but these cuts of meat are seldom eaten by the general public.”
Experimental drug protocol demonstrates reversal of epigenetic aging.
“Research from epigenetics expert Steve Horvath is the first to demonstrate the reversal of epigenetic aging and immunosenescence of the thymus with drug therapy. The thymus is an immune organ necessary for the development of T cell populations.”
Immune cells present in a mother's breast milk enter the infant's thymus & form part of the baby's immune system.
“The research, which used mice, showed that vaccinating the mother resulted in vaccination of the baby through this process of transferring maternal immune cells which then guide the infant's immune cells to attack the same infectious organisms to which the mother has been exposed.”
Episode
Peter Diamandis, MD, and Tony Robbins: Strategies that promote longevity now – and in the very near future
“Placentas are excellent sources of multipotent stem cells because they haven't been subjected to immune "training" in the thymus and aren't associated with the ethical concerns of other stem cell sources.”
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