FoundMyFitness library
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“Our brains shrink as we grow older, but that doesn't mean you can wait until old age to worry about it—neurodegeneration starts 15–20 years before the onset of symptoms of mild cognitive impairment, dementia, or Alzheimer's disease.”
“Another study in which 22 year old men who engaged in four weeks of high-intensity interval training three days a week and supplemented with 150 milligrams of resveratrol per day, the lowest dose of the studies mentioned so far, did not promote increases in the men's aerobic or anaerobic capacity, exercise substrate utilization, or muscle fiber-specific adaptations compared to exercise alone.”
“Interestingly, a recent randomized controlled trial showed that pregnant women who supplemented with 600 milligrams of DHA during their third trimester had sons with larger total brain volumes, total gray matter, corpus callosum, and cortical volumes when compared to boys born to mothers who took a placebo.”
“Taking it a step further, they investigated how sodium and potassium impact blood pressure in men and women differently—a critical question since cardiovascular diseases disproportionately affect men compared to women due to differences in nitric oxide bioavailability, inflammation, electrolyte balance, and sympathetic nervous system activity.”
“In addition, a randomized, placebo-controlled, double-blind trial involving people diagnosed with mild-to-moderate dementia due to Alzheimer's disease found that participants who took a resveratrol supplement twice a day (up to 1 gram) for one year exhibited reduced levels of MMP9, a neurological inflammatory marker associated with increased neurodegeneration and inflammation.”
Small vessel disease is a generic term that describes dysfunction of blood vessels that occurs with aging and contributes to cognitive decline, cardiovascular disease, frailty, and stroke.
“After taking into account other factors, including age, race/ethnicity, poverty/income, tobacco and alcohol consumption, and physical activity, the authors also found that participants with overweight and obesity were nearly four times more likely to have low serum testosterone compared to lean males, independent of SSB consumption.”
“Robust evidence from epidemiological, clinical, rodent, and in vitro studies has demonstrated that sulforaphane exhibits antioxidant and anti-inflammatory properties and may be beneficial against a wide range of chronic and acute diseases, including autism, cancer, metabolic dysfunction, and many others and may ameliorate some of the harmful effects associated with exposure to air pollution.”
“Just one month after their heart attack, participants assigned to 16:8 time-restricted eating experienced a 6.6% increase in a measure of their heart’s pumping efficiency known as left ventricular ejection fraction (LVEF) compared to a mere 1.5% increase in the regular diet group.”
“UPFs cause metabolic and cognitive changes in less than a week "...just 5 days of a high-calorie diet made the brains of these healthy, normal weight men structurally and functionally similar to people with obesity, and even after cutting the high-calorie foods out of their diet, these changes persisted for at least one week."”