Related Episodes for 13 hour daily fast associated with a 36 percent decrease in breast cancer recurrence | Ruth Patterson

“Researchers have determined that beta-hydroxybutyrate is an endogenous regulator of HDACs and is able to regulate age-related genes such as FOXO3. In this clip, Dr. Eric Verdin discusses the role of beta-hydroxybutyrate in protecting against oxidative stress, both as a nutrient, but also as a transcription regulator.”

“For instance, while the U.S. has high obesity rates, its rates of type 2 diabetes remain modest compared to countries like Singapore, India, and many Middle Eastern nations—populations that, on average, tend to have "fatter fat cells" and therefore develop metabolic complications at lower body mass indices (BMIs).”

“Another study suggests that intermittent fasting combined with exercise training increased serum ketone levels, increased the number of mitochondria in muscle cells, and improved endurance. In this clip, Dr. Mark Mattson describes how fasting and exercise work together to promote brain health.”

“In this video, Dr. Darya & Kevin Rose talk about beta-hydroxybutyrate, an endogenous ketone body that increases in concentration during times of fasting or carbohydrate restriction. Beta-hydroxybutyrate also increases during a fasting-mimicking diet, which is a time of temporary period of calorie and protein restriction that generates many of the same biochemical effects of prolonged fasting.”

“Research has identified a few biohacks – lifestyle strategies that improve health and lifespan – that may extend telomeres. The goal of these strategies, which include mindfulness, yoga, exercise, and meditation, is to reduce psychological stress and provide the mind and body periods of restoration and healing.”

“In a separate analysis of seven intervention trials involving people with type 2 diabetes, HbA1c fell by about 0.71 percentage points, total cholesterol by 23 mg/dL, and LDL cholesterol by 22 mg/dL.”

“He observed that in most cases, metabolic rates were a reflection of body mass and closely tracked estimations from predictive equations. In this clip, Dr. Ray Cronise emphasizes the importance of diet to improve healthspan rather than employing tricks to boost metabolic rate.”

“Caloric restriction is a sustained reduced intake of approximately 30 percent fewer calories than one would typically eat, whereas periodic fasting is a more extreme deficit, but only for a short duration.”

“These transient stressors induce the expression of genes that process inflammatory molecules. In this clip, Tim Ferriss and Dr. Rhonda Patrick discuss acute versus chronic inflammation and how supplemental antioxidants can negate some of the benefits of exercise.”