Related Episodes for Does coffee induce autophagy? | Guido Kroemer

“Time-restricted eating involves consuming meals within a specific daily time window. However, choosing the optimal time frame for that window is influenced by many factors, the most important of which is circadian rhythmicity, which alters our body's metabolic responses to food.”

“While sanitation and clean drinking water are critical to survival, the over sterilization of our environment may play a role in modulating the human immune system. In this clip, Dr. Charles Raison highlights how ancient practices such as heat exposure, long-distance running, and fasting may promote well-being in the modern world.”

“Researchers in Dr. D'Agostino's laboratory observed a decreased tumor burden and enhanced survival in animals that were provided a ketone supplement, even if they were fed a high-carbohydrate diet.”

“Researchers have determined that beta-hydroxybutyrate is an endogenous regulator of HDACs and is able to regulate age-related genes such as FOXO3. In this clip, Dr. Eric Verdin discusses the role of beta-hydroxybutyrate in protecting against oxidative stress, both as a nutrient, but also as a transcription regulator.”

“In this video, Dr. Darya & Kevin Rose talk about beta-hydroxybutyrate, an endogenous ketone body that increases in concentration during times of fasting or carbohydrate restriction. Beta-hydroxybutyrate also increases during a fasting-mimicking diet, which is a time of temporary period of calorie and protein restriction that generates many of the same biochemical effects of prolonged fasting.”

“Research has identified a few biohacks – lifestyle strategies that improve health and lifespan – that may extend telomeres. The goal of these strategies, which include mindfulness, yoga, exercise, and meditation, is to reduce psychological stress and provide the mind and body periods of restoration and healing.”

“Three of the most common human diseases are cardiovascular disease, cancer, and Alzheimer's disease. The most significant drivers of cardiac disease are smoking, hypertension and elevated APOB, a biomarker of LDL particle number.”

Alcohol, in particular, can have negative effects on a breastfed infant, including altered sleep patterns, decreased milk intake, and impaired motor development (https://link.springer.com/article/10.1007/s00216-010-3681-0), among others.

“For people concerned about LDL cholesterol, paper-filtered or instant coffee offers a practical way to retain many coffee polyphenols while reducing diterpene exposure. The machine and container also matter.”

“He observed that in most cases, metabolic rates were a reflection of body mass and closely tracked estimations from predictive equations. In this clip, Dr. Ray Cronise emphasizes the importance of diet to improve healthspan rather than employing tricks to boost metabolic rate.”