Ranked by shared topics, with one result from each original episode.
“Insulin-like growth factor-1, or IGF-1 for short, is a protein that plays critical roles in major growth pathways in the human body. It influences nearly every tissue in the body, especially developmental growth, skeletal muscle and neurons.”
“The decline of deep sleep begins early in life, nearly disappears by age 80, increasing the risk for Alzheimer's disease. These Aliquot segments feature Dr. Charles Raison, a professor of psychiatry, and Dr. Matthew Walker, a professor of neuroscience and psychology.”
“These changes drive processes that improve cellular respiration, reduce inflammation, enhance memory, and provide protection from cancer – critical aspects in slowing the effects of aging and promoting longevity. Part II of this three-part Aliquot features Dr. Dominic D'Agostino, an expert in ketosis; Dr. Eric Verdin, an expert in aging; and Dr. Valter Longo, an expert in gerontology.”
“Whereas fasting turns off multiple pathways associated with aging, such as mTOR, IGF-1, growth hormone, and others, eating for optimal fitness activates these important processes. This Aliquot features Drs. Guido Kroemer, Dominic D'Agostino, Valter Longo, Peter Attia, and Rhonda Patrick.”
“The arrival of a new year is a great opportunity to make health-focused resolutions – promises to ourselves that we're going to live better, healthier, and (hopefully) longer. We all age at different rates, however, so our chronological age – the number of years we've lived – often differs from our biological age.”
“Diet stands out as low-hanging fruit for influencing our lifespan. Optimizing macronutrient intake, practicing time-restricted eating, and consuming healthful bioactive compounds are critical aspects of a healthy diet. In part II of this two-part Aliquot, Drs.”
“Since then, the body of research enumerating the profound anti-inflammatory and generalized health-promoting qualities of omega-3s continues to grow; however, some studies fail to show any effects from omega-3 supplementation.”
“Multiple sclerosis (MS) is an autoimmune neurodegenerative disorder that destroys myelin, the insulating layer that surrounds neurons. The causes of MS are complex and may arise from both genetic and environmental factors, including nutritional deficiencies.”
“Exercise is a huge driver of how well we age because it induces profound molecular shifts that support immune health and might even protect our telomeres – indicators of aging. Exercise might help forestall certain age-related diseases, such as Parkinson's disease, too.”
“Roughly one-quarter of people living in the US carry a genetic variant of the apolipoprotein E gene, called APOE4, the most important genetic risk factor for Alzheimer's disease. Many lifestyle behaviors can mitigate risk, especially sleep hygiene, which provides an opportunity to rid the brain of toxic metabolic byproducts that can contribute to Alzheimer's disease risk.”