Fasting associated with sickness behavior critical to surviving bacterial infection | Guido Kroemer

Parent Episode: Dr. Guido Kroemer on Autophagy, Caloric Restriction Mimetics, Fasting & Protein Acetylation

A commonly observed behavior among mammals is the so-called "sickness behavior," where a person or animal that is sick will retreat, avoiding food and contact. This abstention from food induces autophagy and may serve as a means to modulate the body's inflammatory response. Artificially reversing this process in the laboratory – providing nutrients to sick animals – has proven fatal. In this clip, Dr. Guido Kroemer describes how fasting associated with sickness behavior is critical to surviving infection.

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