What is autophagy? Degradation, recycling, and a beneficial response to stress | Guido Kroemer

Parent Episode: Dr. Guido Kroemer on Autophagy, Caloric Restriction Mimetics, Fasting & Protein Acetylation

Autophagy is a highly conserved adaptive response to stress during which a cell gathers unnecessary or damaged cellular components such as protein aggregates, pathogens, or organelles into vesicles and delivers them to lysosomes for destruction. In the process, proteins, lipids, carbohydrates, and nucleic acids are released and become available for energy and re-use. Autophagy's overarching goal is to maintain cellular homeostasis in the face of changing conditions and stress. In this clip, Dr. Guido Kroemer describes the spectacular biological phenomenon known as autophagy.

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