“Sulforaphane, an isothiocyanate compound derived from broccoli sprouts and certain cruciferous vegetables, exerts a wide range of beneficial effects in humans. Some of these effects are mediated by increased glutathione, one of the body's most potent antioxidants, to promote brain health.”
“Mitochondria are best known for their energy-producing roles, but they also help regulate cellular metabolism, signaling, and apoptosis (programmed cell death). As a result, mitochondrial health is intrinsically linked to overall health.”
“Mitochondrial health and overall health are intrinsically linked. Identifying ways to boost mitochondrial biogenesis – the formation of new mitochondria – ensures that cells maintain an adequate number of mitochondria to meet their energy needs.”
“A key component in these processes is the lactate shuttle – a metabolic pathway that facilitates the movement of lactate between tissues so it can be used as an energy source, effectively recycling it and supporting sustained exercise performance.”
“Imagine a drug that improves sleep, reduces stress, sharpens focus, and boosts mood—without cost or side effects. That "drug" is light. Natural light is more than just illumination; it's a potent regulator of our body's internal clock, driving critical processes like hormone release and sleep-wake cycles.”
“Cognitive enhancement is a hot topic, but the best ways to sharpen focus, boost motivation, and support brain health aren't always clear-cut. Stimulants like nicotine and caffeine offer immediate benefits but come with trade-offs—some minor, others riskier.”
“But with their rise in popularity come important questions about long-term effects and safe use. In this Aliquot, I discuss how these drugs work, their pros and cons, the latest research, and lifestyle strategies to optimize their effects for long-term health.”
“In Aliquot #131, The Muscle and Bone Benefits of Creatine, creatine expert Dr. Darren Candow and I discussed how creatine supplementation affects muscle quality, physical function, and even skeletal health, particularly in older adults.”
“In this Aliquot, I'll explore how to recognize and address iron deficiency, the unique challenges of iron overload in aging, the ways alcohol may influence brain iron, and how infants tightly regulate iron as a built-in defense against infection.”
“Jet lag often shows up as fatigue after a long flight, reflecting a mismatch between your internal clock and the external world. In this Aliquot, joined by Drs. Michael Grandner and Darren Candow, I explain how jet lag works, which signals are most important for resetting your clock, and how to reduce jet lag before travel and recover more quickly after arrival.”