Related Episodes for What can you do to preserve telomere length (and what to watch out for) | Elissa Epel

“Vitamin D and a home exercise program added benefit on one clock. Separate analyses found lower odds of prefrailty and fewer invasive cancers with the full three-part intervention, making the combined healthy-aging approach a useful area for continued study.”

“In the prospective Framingham Offspring Study, people in the highest red-blood-cell DHA group had approximately 49 percent lower risk of developing Alzheimer's disease than those in the lowest group.”

“The PROT-AGE Study Group recommends at least 1.0 to 1.2 grams of protein per kilogram of body weight per day for most adults over 65 to help maintain lean mass and physical function. Longitudinal evidence connects higher protein intake with better muscle and frailty outcomes.”

“Melatonin appears in the comparison as a personal, goal-specific choice rather than a universal nightly supplement. Dr. Patrick also discusses glycine, collagen, myo-inositol, and other non-overlapping items with different levels of evidence.”

“A 2025 network meta-analysis of 217 randomized trials and 15,684 people with knee osteoarthritis found that aerobic exercise was likely the most beneficial exercise category for pain, function, gait, and quality of life.”

“A second randomized trial found that a single vitamin D3 dose taken with food increased vitamin D status, with a larger rise when the meal contained at least 15 grams of fat. These findings support taking vitamin D with a meal that contains some fat.”

“In this clip from Dr. Rhonda Patrick's appearance on Next Question with Katie Couric, she explains how sustained exercise can improve cardiovascular fitness and the heart's ability to fill efficiently during middle age.”

“In later randomized trials, urolithin A improved some laboratory measures of muscle endurance or hamstring strength, but it did not significantly improve key primary outcomes such as six-minute walk distance, muscle ATP production, or peak power.”

“Large treadmill cohorts associate higher measured fitness with lower mortality, while a 46-year study of middle-aged men linked the highest fitness category with about 4.9 additional estimated life-years compared with the lowest category.”

“Reversing the Cardiac Effects of Sedentary Aging in Middle Age—A Randomized Controlled Trial - In sedentary middle-aged adults, 2 years of regular exercise improved heart function and reduced heart stiffness, potentially lowering future heart failure risk.”