Related Episodes for Women AND men’s health prior to conception affects offspring | Elissa Epel

“In a small immobilization trial, five grams per day of omega-3 fatty acids reduced the loss of muscle volume in young women compared with sunflower oil, supporting continued research on omega-3s and disuse atrophy. Heat is the fourth proposed tool.”

“The question of whether NAD+ is derived directly from NR or NMN in certain tissues rather than being salvaged from nicotinamide may, in particular, have implications for whether or not oral administration may be hampered in achieving maximal NAD+ status due to the fact that the process of salvaging NAD+ from nicotinamide is subject to feedback inhibition.”

“Dr. Patrick also discusses vitamin D and potassium as nutrients that are commonly worth assessing. Vitamin D status varies with sun exposure, diet, skin pigmentation, age, and body composition, while potassium-rich foods help support blood-pressure regulation.”

“A randomized-trial meta-analysis found a higher atrial-fibrillation risk with marine omega-3 supplementation, with a stronger signal at doses above 1 gram per day; the included populations generally had cardiovascular disease or elevated cardiovascular risk.”

“EPA and DHA play particularly important roles in heart health because they participate in pathways involved in the production of hormones that regulate blood clotting and inflammation, help maintain healthy heart rhythms, and influence the contraction and relaxation of arteries.”

“Dr. Bruce Ames' Triage Theory Dr. Ames proposed that the body does a strategic rationing so that those proteins and enzymes in the body which are essential for short-term survival get their share of vitamins and minerals at the expense of other proteins and enzymes that are essential for long-term survival.”

“Dr. Patrick also discusses STEP 5, in which two years of treatment produced about 15.2 percent loss versus 2.6 percent with placebo, with the curve leveling while participants remained on treatment. Dual GIP/GLP-1 therapy can produce still larger losses in some trials.”

“A few examples of genes with common polymorphism discussed are MTHFR and folate, NBPF3 and vitamin B6, FUT2 and vitamin B12, BCMO1 and beta-carotene, FADS2 and omega-3 fatty acids, CYP2R1 and vitamin D, PEMT and choline as well as APOE4 and FOXO3.”

“A special focus of this podcast, however, centers on Pierre's relationship with previous podcast guest Wim Hof, who is especially well-known for his extraordinary ability to withstand extreme cold, taking on many world records by doing so.”

“Using containers intended for hot food, replacing badly worn plastic utensils, avoiding overheating damaged nonstick cookware, and choosing reusable drinkware are low-burden ways to reduce avoidable contact.”