Related Episodes for Ketone effects on the brain: APOE-4, vascular dementia, ischemia and epilepsy

“Jet lag often shows up as fatigue after a long flight, reflecting a mismatch between your internal clock and the external world. In this Aliquot, joined by Drs. Michael Grandner and Darren Candow, I explain how jet lag works, which signals are most important for resetting your clock, and how to reduce jet lag before travel and recover more quickly after arrival.”

“In this Aliquot, I'm joined by Drs. Martin Gibala, Luc van Loon, and Brad Schoenfeld to break down how to manage load, train in joint-friendly ways, reduce inflammation, and separate supplements supported by evidence from those that remain uncertain.”

“These changes increase infection risk, weaken vaccine responses, and reduce early cancer surveillance. Yet immune aging is not fixed. Movement, sleep, stress regulation, temperature exposure, and nutrition shape immune cell balance and inflammatory activity over time.”

“In this Aliquot, I explain why visceral fat behaves so differently from other fat, how it drives insulin resistance and chronic disease, and what research shows about the most effective ways to reduce it.”

“In this Aliquot, I walk through how that plays out in humans, where the strongest evidence shows up, and where it doesn't, with NAD researcher Dr. Charles Brenner—and why I'm taking it now after being skeptical.”

“Physical activity, sleep, light exposure, heat, and certain nutrients may all affect systems involved in mood regulation, including inflammation, circadian rhythms, neuroplasticity, and brain energy metabolism. In this Aliquot, Drs.”

“And one potential strategy for mitigating our risk for Alzheimer's disease as we age is a "cognoscopy" – a battery of assessments that measures some of the key biomarkers associated with the disease and can inform the trajectory of treatment.”

“Scientists have also identified interesting links between depression and obesity – likely mediated by elevated inflammation, since fat cells produce a wide array of inflammatory factors. In this Aliquot segment, psychiatrist Dr. Charles Raison describes the links between inflammation and depression.”

“Zinc is an essential nutrient that participates in many biological processes and plays critical roles in immune function, protein synthesis, wound healing, DNA synthesis, cell division, and brain health.”

“Acute activation of the immune system (from exercise or sauna use for example) can temporarily reduce inflammation and the depression that can come with it. The segments brought to you by this episode of The Aliquot feature professor of psychiatry Dr. Charles Raison.”