Related Episodes for Bruce Ames on the importance of maintaining optimal vitamin D levels

“The most compelling human signal appears when the brain is under acute strain. In a randomized crossover study, a single dose of 0.35 grams per kilogram during 21 hours of sleep deprivation changed cerebral energy metabolites and preserved selected measures of cognitive performance.”

“Tools, companies, and resources mentioned OpenAI - AI research and deployment company behind widely used GPT systems and developer tools; its science case study describes GPT-5 helping Unutmaz's lab resolve a long-standing immunology question.”

“Her practical message is to reduce the frequency and size of large glucose exposures. Foods with intact fiber, protein, and minimally processed carbohydrates digest more slowly than refined added sugar, while regular exercise gives skeletal muscle a large destination for circulating glucose.”

“Sure, those dates on the calendar pass at the same rate for everybody, but some people appear to age slower (or faster) than others – with vastly different age-related physical changes and disease risks.”

“Controlled human studies support acute brain-related responses to high-intensity exercise. Six short all-out cycling intervals improved selected learning and executive measures while increasing circulating BDNF, IGF-1, and VEGF; lactate tracked several of these changes.”

“Studies of centenarians suggest that lower levels of inflammation are associated with longevity. Different types of fiber provide fuel to diverse species of bacteria in the gut, which then synthesize byproducts that regulate the inflammatory process.”

“Dr. Patrick recommends vigorous intervals when moderate training does not improve an individual’s VO2 max and presents repeated one-minute efforts and the Norwegian 4-by-4 as practical options.”

“Dr. Patrick explains some of the early evidence that suggests the value prolonged fasting (48+ hours) may have from the standpoint of tissue rejuvenation and healthspan maintenance, as well as relevance for other more specific conditions.”

“In this clip, Dr. Valter Longo discusses the origin of the fasting-mimicking diet and a possible future which may lean away from a drug-centered mentality to one which allows the body to heal itself.”

“People with Parkinson's disease can benefit from engaging in an intense exercise program that incorporates both a skilled and an aerobic component. Activities that involve gait and balance training are particularly useful.”