Related Episodes for MTHFR gene and supplementation with 5-L-methylfolate | Tim Ferriss

Jim Kean is the CEO of National Pro Grid League (NPGL) and founder of WellnessFX.

“Study. 01:43:00 - High animal protein intake was only positively associated with cardiovascular mortality among individuals with at least one unhealthy lifestyle risk factor, such as obesity or sedentary lifestyle. Study.”

“00:29:20 - Organs shrink during fasting and then regrow after refeeding. Study. 00:29:45 - Fasting stresses healthy cells so they increase their stress-response pathways, including heat shock proteins, antioxidant production, and anti-inflammatory.”

“02:03:18 - A recent study measured omega-3 fatty acid levels from both supplemental and dietary sources in blood and found that for every 1 percent increment in omega-3 fatty acid levels there was a 20 percent decreased risk in all-cause mortality.”

“Dr. Patrick also discusses glucose, HbA1c, fasting insulin, kidney and electrolyte markers, hs-CRP, fibrinogen, thyroid tests, CBC, vitamin D, sex hormones, IGF-1, and the Omega-3 Index.”

“If we eat carbohydrate-containing foods when melatonin levels are high, our pancreas cannot produce the insulin needed to use the glucose. Therefore, eating too close to bedtime or immediately upon waking, before nightly melatonin levels have declined, may hamper the body's ability to process glucose.”

“Finally, choline is also a precursor for phosphatidylcholine, the major component of all cell membranes, which affects the structure, permeability and function of cells and is particularly important in neurons since it plays a role in general neurotransmission.”

“A higher omega-3-index quintile was associated with lower all-cause mortality risk, but the estimated years of life were model-derived comparisons between quintiles, not observed gains from raising an index from 4% to 8%.”

“A later Framingham analysis followed 2,240 adults for 11 years and found that a red-cell fatty acid model including the Omega-3 Index predicted all-cause mortality about as well as a model using several standard cardiovascular risk factors.”

“Direct graded exercise testing in an accredited lab is the reference method because it measures oxygen uptake and also reports heart rate, power, lactate, and training-zone data. Dr. Gibala describes submaximal tests as the middle tier.”