Related Episodes for Why the phytochemicals in plants may be better than the antioxidants | Dr. Mark Mattson

“Creatine works by building tissue stores, so consistent daily intake matters more than taking it immediately before a specific workout. Dr. Patrick and Dr. Candow also discuss its value during aging, when preserving training quality and muscle becomes increasingly important for function and independence.”

“However, vegans and vegetarians frequently have higher levels of other micronutrients, such as vitamins C and E. Getting the required micronutrients is essential for maintaining optimal health when following a vegan diet.”

“Moreover, taking mega doses (i.e. 400 IU/day) of alpha tocopherol has the unintended side-effect of actually depleting tissue levels of another important form of vitamin E that plays an anti-inflammatory role, known as gamma tocopherol.”

“Conventional health advice, such as healthy eating, physical activity, and education level are linked with slowed epigenetic aging, albeit weakly, and obesity, sleep deprivation, and smoking are linked with accelerated epigenetic aging.”

“A small exploratory study detected some phthalates and metabolites in sweat, but it did not test sauna or exercise, show a fall in body burden, or establish clinical benefit. Reducing exposure remains the clearest practical strategy.”

“In a crossover experiment with 12 healthy adults, six 40-second high-intensity cycling intervals increased circulating BDNF four to five times more than 90 minutes of light cycling. The BDNF response also tracked with the rise in circulating lactate.”

“Patients assigned to supervised exercise during neoadjuvant chemoradiation, followed by continued activity before surgery, were more likely to achieve a complete or near-complete pathological response than those receiving usual care.”

“A larger randomized-trial meta-analysis also found modest average reductions in BMI, waist circumference, and body-fat percentage, although protocols and populations varied. These averages do not mean that HIIT alone guarantees fat loss.”

“The physical activity guidelines and estimates on how much activity we need are heavily based on self-reported activity, which is useful but imperfect: people remember going for a run, but they forget the short, intense bursts in daily life like sprinting up stairs, chasing kids, and running to catch a bus.”

“Dr. Patrick describes increased shear as a possible way vigorous exercise can damage fragile circulating tumor cells; this is a proposed mechanism, not proof that a workout eliminates metastasis or treats an established tumor.”