Ranked by shared topics, with one result from each original episode.
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“A small one-year randomized trial in older adults appeared to buffer decline on a verbal-learning task and increased activation in selected frontal regions; the result needs replication and does not establish broad cognitive enhancement.”
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“The fact that poor sleep is linked with the aggregation of amyloid-beta plaques in the brain and Alzheimer's disease is not surprising. Although some strategies for improving the quality of sleep among people with Alzheimer's have been identified, this might be too late to turn the tide of cognitive decline.”
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“Removing former drinkers from the non-drinker category reveals a different story: One study observed that the lowest risk for cardiovascular disease (i.e., ischemic heart disease) was right below one standard U.S. drink per week — men and women at this level of consumption had an ~18% lower risk compared to nondrinkers.”
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“Vasopressin, a pituitary hormone that acts to promote the retention of water by the kidneys and increase blood pressure, is also a social bonding hormone in males — similar to oxytocin in females. Tim recounts his experiences taking vasopressin in college to boost his short term memory.”
“Sulforaphane, an isothiocyanate compound derived from broccoli sprouts and certain cruciferous vegetables, exerts a wide range of beneficial effects in humans. Some of these effects are mediated by increased glutathione, one of the body's most potent antioxidants, to promote brain health.”
“A key component in these processes is the lactate shuttle – a metabolic pathway that facilitates the movement of lactate between tissues so it can be used as an energy source, effectively recycling it and supporting sustained exercise performance.”
“In Aliquot #131, The Muscle and Bone Benefits of Creatine, creatine expert Dr. Darren Candow and I discussed how creatine supplementation affects muscle quality, physical function, and even skeletal health, particularly in older adults.”
“In this Aliquot, I'll explore how to recognize and address iron deficiency, the unique challenges of iron overload in aging, the ways alcohol may influence brain iron, and how infants tightly regulate iron as a built-in defense against infection.”
“Jet lag often shows up as fatigue after a long flight, reflecting a mismatch between your internal clock and the external world. In this Aliquot, joined by Drs. Michael Grandner and Darren Candow, I explain how jet lag works, which signals are most important for resetting your clock, and how to reduce jet lag before travel and recover more quickly after arrival.”
“In this Aliquot, I explain why visceral fat behaves so differently from other fat, how it drives insulin resistance and chronic disease, and what research shows about the most effective ways to reduce it.”