Ranked by shared topics, with one result from each original episode.
“Individual responses to diet can be influenced by a person's genetic makeup, however. Knowing a person's genetic factors influencing their response to diet may be beneficial component of a multi-part strategy developed in coordination with professional care for keeping ApoB in check.”
“Lifestyle factors, such as exercise, nutrition, sleep, and others, can temper some of the risks associated with carrying APOE4. This Aliquot focuses on the ones that can have the greatest benefits – and the ones that do the most harm.”
“When it comes to managing inflammation, we often focus on what lifestyle habits we might need to get rid of, but it's just as important to focus on things we can add to our lifestyles. In this Aliquot, we'll talk about my top recommendations for lifestyle habits that reduce inflammation.”
“Vascular dysfunction, the loss of normal endothelial tone and permeability of blood vessels, is a common feature of most forms of dementia, including Alzheimer's disease. People who carry the APOE4 gene are at greater risk for vascular dysfunction and Alzheimer's disease.”
“Preventing dementia requires a lifelong and multipronged approach that involves keeping inflammation (and its aging effects) at bay and making healthy lifestyle choices, such as exercising and consuming omega-3 fatty acids.”
“Genetic predisposition, altered glucose uptake in the brain, high blood pressure, and other factors can weaken the barrier's integrity, allowing endotoxins and inflammatory immune cells to infiltrate the brain and increasing a person's risk for dementia.”
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“Early biomarkers of vascular dysfunction, such as soluble platelet-derived growth factor receptor-beta (sPDGFR-β), can help identify individuals at risk for developing Alzheimer's disease. These biomarkers are being validated on high-throughput platforms for large-scale testing.”
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“For people whose ApoB rises on a high-saturated-fat diet, replacing butter, cheese, fatty red meat, coconut oil, and palm oil with olive oil, avocado, nuts, and fish is a practical experiment to review with a clinician.”
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“Approximately 25 percent of people living in the United States carry a genetic variant of this lipoprotein called APOE4, which is associated with higher circulating levels of LDL cholesterol and an increased risk for Alzheimer's disease.”
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“The ketogenic diet is contraindicated in people with pancreatitis, fat metabolism disorders, and other rare metabolic conditions. Some people carry a version of the apolipoprotein E gene called APOE4 – a risk factor for late-onset Alzheimer's disease.”