Related Episodes for What Alpha-Lipoic Acid Does in Metabolism

“00:34:40 - Repeated traumatic brain injury has cumulative neuroinflammatory effects in the brain over years, including amyloid-beta plaque and tau tangle formation. Study. 00:44:00 - A variant of the APOE gene increases risk of developing Alzheimer’s disease as much as 15-fold.”

“New Scientist article. 02:06:10 - Some people, like Tom Cruise and Keanu Reeves, seem to defy aging. 02:08:15 - One 12-ounce can of sugar-sweetened soft drink per day shortened telomere length, corresponding to 4.6 years of biological aging.”

“Some of the factors contributing to these variable phenotypes include persistent damage to our DNA and mitochondrial dysfunction, driven by an altered NAD:NADH ratio, the latter of which has recently been shown to be improved by certain dietary supplements like nicotinamide riboside.”

“In addition, exercise preferentially causes the brain to take up lactate. Dr. Attia discusses some interesting research from several decades ago that uncovered the shifts in metabolism that occur in the human body and brain upon extreme fasting.”

“If your magnesium levels are inadequate, then your ability to boost mitochondrial number during HIT will be dampened, thus, compromising performance and the mitochondrial mass you would have otherwise gained as a consequence of your hard work and effort.”

Dr. Michael Snyder discusses personalized medicine and the use of technologies that monitor metabolism and other health markers.

“A meta-analysis of resistance-training trials found that protein supplementation produced modest additional gains in strength and fat-free mass, with average fat-free-mass benefit plateauing near 1.62 g/kg/day. This is a group estimate, not a precise requirement for every older adult.”

“Researchers believe incorporating these fatty acids into mitochondrial membranes might alter ADP handling and oxygen utilization, potentially affecting muscle protein synthesis and energy production.”

“It remains unknown whether these levels are sufficient for optimal immunological functioning. A large meta-analysis of 32 studies, spanning nearly 50 years, suggests that 25-hydroxyvitamin D levels below 30 ng/mL are associated with a higher risk of death from all causes.”

Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.