Related Episodes for Why Vitamin D Deficiency Accelerates Brain Aging

Many of the anabolic effects of growth hormone are thought to be mediated by insulin-like growth factor-1, or IGF-1 (https://www.ncbi.nlm.nih.gov/pubmed/18500379), which is synthesized primarily in the liver but also in skeletal muscle in response to growth hormone.

“00:29:20 - Organs shrink during fasting and then regrow after refeeding. Study. 00:29:45 - Fasting stresses healthy cells so they increase their stress-response pathways, including heat shock proteins, antioxidant production, and anti-inflammatory.”

“00:34:40 - Repeated traumatic brain injury has cumulative neuroinflammatory effects in the brain over years, including amyloid-beta plaque and tau tangle formation. Study. 00:44:00 - A variant of the APOE gene increases risk of developing Alzheimer’s disease as much as 15-fold.”

“Dr. Patrick recommends bounded quality checks such as GMP manufacturing and independent testing; she notes that some tested products were below their stated heavy-metal limits, not that lion’s mane products are uniformly contaminated.”

“A later Framingham analysis followed 2,240 adults for 11 years and found that a red-cell fatty acid model including the Omega-3 Index predicted all-cause mortality about as well as a model using several standard cardiovascular risk factors.”

“Some people with primary sleeping disorders use melatonin to help them fall asleep. While some research indicates that melatonin helps with sleep latency — or the ability to fall asleep — it may not support a person's ability to stay asleep.”

“Assessing and quantifying the exposome — all of the non-genetic tangible exposures we experience during a lifetime, including those from the air, physical surroundings, microbes, and chemicals — is challenging.”

“A randomized-trial meta-analysis found a higher atrial-fibrillation risk with marine omega-3 supplementation, with a stronger signal at doses above 1 gram per day; the included populations generally had cardiovascular disease or elevated cardiovascular risk.”

“Dr. Bill Harris shares his nuanced insights into whether omega-3 supplementation carries a bleeding risk. Dr. Harris bases his understandings on observations from clinical trials using extreme dosages, additional research that directly contradicts omega-3 intake as a generalized concern for bleeding risk during surgery, as well as comments from the FDA.”

“Parkinson's disease is a progressive neurodegenerative disorder with no cure. The disease, which typically manifests later in life, is caused by the destruction of neurons that produce dopamine — a neurotransmitter best known for its role in motor, motivation, and pleasure control.”