What FoundMyFitness Has Covered
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Aliquot #132: Mitigating the Harms of Air Pollution
“Air pollution leaves a biological fingerprint on our lungs, our blood vessels, and even our brains, eroding the body's defenses, triggering inflammation, weakening the blood-brain barrier, and accelerating cognitive decline.”
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Sulforaphane increases detoxification of air pollutants | Jed Fahey
“Robust clinical evidence has demonstrated that sulforaphane increases the production of mercapturic acid metabolites of benzene and acrolein, known carcinogens present in air pollution and smoke from fires.”
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Sulforaphane and benzene detoxification (relevance in smokers and for air pollution) | Jed Fahey
“A 2014 study found that sulforaphane from a broccoli sprout beverage markedly increased urinary benzene excretion among people living in China, where air pollution levels are among the highest in the world.”
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Sulforaphane boosts detoxification of air pollutants benzene and acrolein | Rhonda Patrick
“Recent clinical evidence suggests that sulforaphane can help the body to rapidly excrete potential cancer-causing compounds, such as benzene and acrolein, which are prevalent in air pollution and cigarette smoke.”
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How Sulforaphane Activates Cellular Defense Pathways
“In a 12-week randomized trial of 291 adults living in a region of China with substantial air pollution, a broccoli-sprout beverage increased urinary excretion of a benzene metabolite by 61 percent and an acrolein metabolite by 23 percent.”
Blood-brain barrier
“Autopsy findings revealed elevated levels of amyloid and tau proteins in 202 out of 203 young brains, including an 11-month-old baby. Preclinical evidence suggests a role for toll-like receptor 4 (TLR4) activation in air-pollution-induced neuroinflammation.”
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How Sulforaphane Supports Glutathione and Detoxification
“In a 12-week randomized trial of 291 adults exposed to substantial air pollution, a broccoli-sprout beverage increased urinary excretion of glutathione-derived conjugates of benzene by 61 percent and acrolein by 23 percent compared with placebo.”
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Managing and detecting the exposome and exposure to air pollution | Dr. Michael Snyder
“Assessing and quantifying the exposome — all of the non-genetic tangible exposures we experience during a lifetime, including those from the air, physical surroundings, microbes, and chemicals — is challenging.”
Microplastics
“Get involved in community clean-up efforts and support companies that prioritize sustainability. Mitigating microplastic pollution Given the widespread environmental burden of microplastics, finding effective removal strategies has become crucial.”
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