Search results for exercise

“Dopamine replacement drugs, such as levodopa, alleviate motor symptoms of the disease, but people often experience side effects over time. In clinical reports, those who decline dopamine replacement often experience excessive fatigue rendering them unable to exercise and gain its benefits.”

“Similarly, the timing of eating and exercise, especially in elite athletes, has not been studied and may, in fact, require self-experimentation by the athletes as they find the perfect interval of fasting to support their optimal performance. In this clip, Dr. Satchin Panda discusses the limited data available today regarding dietary supplement usage, exercise, and time-restricted eating.”

“Exercise stresses the entire body – the heart, lungs, bones, muscles, and even the brain. The body responds by inducing a wide range of adaptations that increase its ability to cope with the stressor.”

“During intense exercise, while hormones stimulate fat breakdown, the muscle's enhanced mitochondrial capacity determines fat oxidation. In this clip, Dr. Martin Gibala outlines the relationship between exercise types, mitochondrial growth, and their combined effect on fat metabolism.”

“Having someone to provide feedback is important to help the person progress and stay engaged. In this clip, Dr. Giselle Petzinger describes her recommended components for an exercise program for people with Parkinson's disease.”

“For example, high-intensity exercise such as long-distance running is linked to an increased incidence of upper respiratory infection. Conversely, evidence suggests that reactive oxygen species might also mediate beneficial training adaptations as a part of a biologically useful signaling cascade.”

In this clip, Dr. Patrick explains how intense exercise beneficially alters tryptophan and kynurenine metabolism in a way that may benefit depression.

“Several randomized controlled trials have suggested that metformin blunts some of the positive effects of aerobic exercise and strength training. Healthy adults taking metformin exhibited 50 percent less improvement in cardiorespiratory fitness following an exercise program.”

“The randomized trial assigned healthy sedentary adults aged 45 to 64 to two years of progressive exercise or an attention-control program. Training increased VO2 max by about 18 percent and reduced left-ventricular stiffness.”

“Eating prior to participating in shorter training periods, however, blunts the beneficial effects associated with training in the fasted state, especially those associated with enhanced mitochondrial fatty acid oxidation. In this clip, Dr. Rhonda Patrick discusses the circumstances under which eating prior to exercise is beneficial versus detrimental.”