Search results for mitochondria

“Oxidative stress occurs during the process of oxidative phosphorylation (the generation of energy) in mitochondria and can be reflective of exposures to both physical and psychological stressors. Evidence suggests that depigmented hairs may exhibit altered mitochondrial energy metabolism.”

“NAD+ is a cofactor for many metabolic enzymes and becomes depleted across various tissues as we age. This causes the mitochondria to suffer and mitochondrial decay is also thought to also be a key driver of aging.”

“This causes the mitochondria to suffer and mitochondrial decay is also thought to also be a key driver of aging. To learn more about the role of nicotinamide riboside and NAD+ in aging...check out my conversation with Dr. Eric Verdin.”

“Markers of amino acid breakdown, including 2-hydroxybutyric acid and 2-oxobutyric acid, were also elevated in Parkinson's disease patients, suggesting that protein-derived fuels may contribute more to energy supply in Parkinson's disease.”

“In a previous study, this team of researchers discovered that avocatin B accumulates in mitochondria of leukemia cells, inhibiting fat oxidation, and inducing cell death. The researchers conducted their study in three phases, including a trial in mice, a laboratory study of pancreatic cells, and a trial in humans.”

“One possible explanation for these findings is that the photons delivered through PBMT may be absorbed by cytochrome c oxidase, an enzyme found in mitochondria, the parts of cells that help convert nutrients into usable energy.”

“Additionally, the muscle's capacity to use oxygen, a key indicator of cardiorespiratory fitness, dropped by as much as 45 percent. The study investigators attributed this decline to the statin's inhibition of specific components (complexes III and IV) within the mitochondria that are vital for energy production.”

“01:57:05 - Rhonda explains the process of mitophagy – the clearing away of damaged mitochondria. 01:58:40 - The trend of using transfused blood from young people to slow aging. 02:04:20 - GDNF-11, a growth factor in young people's blood, may slow aging.”

“Rhonda discusses how cold exposure increases norepinephrine up to 5-fold in the brain and what the temperature and duration needed to do this are, how norepinephrine has an effect on mood, vigilance, focus, and attention, how cold exposure increases cold shock proteins including one in the brain that repairs damaged synapses and in muscle prevents atrophy…”

“Ketone bodies can cross the blood-brain barrier to enter the brain and neuronal mitochondria, where they provide essential energy. Dr. Mattson describes an added bonus of ketones: They burn "cleaner" than glucose, yielding fewer free radicals during their metabolism.”