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Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.

Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.

Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.

“Eating a typical Western diet – high in processed foods and sugar-sweetened beverages – raises blood glucose and insulin levels, promotes inflammation, and contributes to many neurological disorders, including Alzheimer's disease.”

“To look for functional mitochondrial effects, Dr. Attia uses controlled Zone 2 work while sampling lactate, with output near 2 mmol/L. He says statins have not produced the clear lactate-performance changes he sees with metformin.”

“The use of alternate fuel sources allows glucose to be spared for the metabolic pathways that require it. In this clip, Dr. Dominic D'Agostino discusses the metabolic flexibility of the brain to use various substrates, including ketones, for energy.”

“Mitochondrial health and overall health are intrinsically linked. Identifying ways to boost mitochondrial biogenesis – the formation of new mitochondria – ensures that cells maintain an adequate number of mitochondria to meet their energy needs.”

“You may have first heard about Dr. Attia from his two interviews that have been on the Tim Ferriss show, or from any number of popular presentations he's given that were filmed and put online.”

“Smaller crossover studies support the same practical direction. Sprint intervals improved the late insulin response after one four-hour night of sleep, and a two-week HIIT program attenuated the rise in glucose, insulin, and free fatty acids after 24 hours without sleep.”

“Dr. Patrick also explains how lactate signaling and repeated high-intensity work can increase glucose-transport capacity and promote mitochondrial adaptation. Exercise snacks can also turn stairs, walking, and other routine activities into vigorous intermittent lifestyle physical activity.”