Search results for weight loss

“Clinicians diagnose depression as major depressive disorder based on a set of diagnostic criteria including one of two primary symptoms – depressed mood (e.g., sadness, irritability) and/or anhedonia (i.e., loss of interest or pleasure in doing things) – and four or more secondary symptoms – appetite or weight changes; sleep difficulties (e.g., insomnia or sleeping too much)…”

“Weight loss is often part of the primary treatment of type 2 diabetes; however, some weight loss diets may have more insulin-sensitizing effects than others. Findings of one report show that a high protein weight loss diet can reverse prediabetes by increasing insulin-sensitizing hormones.”

“The biology of aging is increasingly seen as treatable, and drugs like semaglutide—once solely used for diabetes and weight loss—may be part of the solution. A recent study found that people with HIV who took semaglutide for 32 weeks experienced up to a 4.9-year reduction in biological age, as measured by changes in DNA methylation.”

“"The present results support a role specifically for colonic propionate in weight management and may provide a molecular explanation of recent data that have observed changes in the gut [range of bacteria] and associated [short chain fatty acid production] profiles in weight loss," researchers conclude.”

“Calorie restriction does more than reduce body fat; it also changes how cells maintain and repair themselves. Researchers investigated whether semaglutide, a GLP-1 receptor agonist widely used for weight loss, could reproduce some of those effects when given late in life.”

“Researchers fed mice a diet that promoted weight gain early in life. Then they studied the effects of having excess body fat on the animals' adipose tissue macrophages – a type of immune cell found in fat. Later, they put the mice on a diet that promoted weight loss.”

“Broad loss of sirtuin activity, potentially due to a reduction in NAD+, is typically observed with aging, and many animal models demonstrate that decreased SIRT1 activity may promote the pathogenesis of cardiovascular and neurological diseases.”

“Lifestyle modifications such as exercise and diet (to promote weight loss) are often recommended as a means to restore testosterone levels. Findings from a new study suggest that eating a lower-fat diet may contribute to low testosterone levels.”

“Recent evidence demonstrates that excess body weight impairs cognitive function. The findings from this study suggest that excess body weight drives gray matter losses similar to those seen in Alzheimer's disease. Read full publication.”