Search results for epigenetics

“These heritable changes, known as epigenetic modifications, do not alter the DNA code itself but can affect how genes are switched on or off during development. While the study relied on self-reported exposure and lacked genetic data, its findings highlight the importance of protecting children from secondhand smoke.”

“Further complicating the picture, a recent pre-print study presented new findings about rapamycin's effects on aging. The study assessed the effects of rapamycin across 16 epigenetic aging clocks and found that it accelerated aging markers in humans.”

“00:02:00 - BPA in plastic bottles is a potential endocrine disruptor. Study. 00:02:30 - BPA has diverse effects on human health, including endocrine, reproductive, and transgenerational epigenetic effects.”

“By attaching to histones, it changes how DNA is packaged, making fat metabolism genes more active. This epigenetic mechanism, meaning a change in gene activity without altering DNA itself, appears to help the body burn more fat and improve metabolic health.”

“For example, methamidophos, a type of pesticide, damaged the barrier and disturbed sperm production in rodents. Similarly, bisphenol AF, a compound used in plastic manufacturing, damaged sperm DNA and induced genetic and epigenetic changes in fish.”

“1 00:46:20 - Human recombinant soluble ACE2 reduced the SARS-CoV-2 infection in engineered human organoid tissues. 1 00:53:33 - Vitamin D supplementation for 16 weeks caused 2 year reduction in epigenetic aging in African Americans.”

“The role of omega-3 fatty acids in resolving inflammation | Rhonda Patrick. Vitamin D and omega-3 may slow epigenetic aging | Steve Horvath. Omega-3s in breast milk may improve brain function in infants | Rhonda Patrick.”

“The authors recognize the need for rigorous meta-analyses to understand the hormonal, epigenetic, and metabolic mechanisms by which acetaminophen affects development in humans. Link to full publication.”

“If confirmed in future studies, biological age measures could help inform prevention and early intervention strategies by identifying biological changes associated with cancer risk earlier in life. In episode #112, I discuss with Dr. Steve Horvath how epigenetic clocks measure biological age and which interventions actually slow or reverse aging.”

“Addressing these hallmarks, which include genomic instability, epigenetic alterations, and loss of proteostasis, among others, is essential to forestalling aging and restoring youthfulness.”