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Dr. Rhonda Patrick explores melatonin's antioxidant properties, curcumin supplementation, antinutrients, and SARMs in her latest Q&A.

“MVPA, defined here as activity comparable to walking at about 4–5 km per hour (2–3 mph), may influence mortality risk through well-established pathways related to cardiovascular function, glucose regulation, and overall metabolic demand, especially when added to near-zero baseline activity.”

“A recent study found that substituting even small amounts of sedentary time with physical activity or sleep reduced the risk of adverse outcomes in the year after a heart attack by more than 60%. Researchers enrolled 609 adults hospitalized for acute coronary syndrome over a four-year period.”

“In the first cohort, they measured vitamin C in the dermis (the deeper, collagen-rich skin layer) and epidermis (the outer, cell-rich skin layer) from 38 adults undergoing elective surgery and related these values to fasting blood levels of vitamin C.”

Dr. Rhonda Patrick discusses protein needs, choline in pregnancy, urolithin A, melatonin's benefits and risks, and creatine's effects on liver health.

“Stable glucose despite lower insulin indicates better insulin sensitivity, while the lower heart-rate response during exercise and faster muscle oxygen recovery suggest more efficient blood flow regulation and oxygen delivery or use.”

“- Arthur Brooks, Ph.D. The episode closes with a framework from Brooks's work on the second half of life: jump, serve, worship, and connect, a framework he outlines in one of his earlier books, From Strength to Strength: "Jump" means proactively building the next thing, especially during liminal periods or unwelcome change, which Brooks sees as fertile ground for creativity.”

Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.

Dr. Rhonda Patrick discusses cancer prevention, linoleic acid, shingles vaccine and dementia, creatine's kidney effects, and shares her overnight oats recipe.

“While it didn't improve cholesterol levels overall, some subgroup analyses showed better results with lower doses (100 milligrams daily or less) and shorter study durations (less than 12 weeks).”