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“Further, they found that the cost-benefit analysis involved in the decision to expend effort occurs early in the decision-making process and can be measured by patterns in gaze (focusing on a reward or cost of a task) during cognitive testing.”

“Researchers measured chair-stand performance as the main outcome, along with other measures of physical function and quality of life, C-reactive protein (CRP, a marker of inflammation), epigenetic age measures (estimates of biological age based on chemical tags on DNA), routine safety blood tests, and adverse events.”

“- Brad Schoenfeld, Ph.D. Highlighting a certain hypocrisy, Dr. Schoenfeld points out that while most parents won't blanch at their children participating in sports that are characterized by real risks of injury, they will often worry themselves unnecessarily about resistance training, which has fewer risks.”

“Regardless of the limitations of current studies in helping to immediately isolate specific drivers of aging, the clocks should provide a means of assessing cellular age under experimental conditions and make possible the direct testing of hypotheses about the causes of aging or the effectiveness of anti-aging interventions.”

“Drinking two to three cups per day is linked to roughly a 60% reduced risk of developing diabetes, a statistic that highlights coffee's robust metabolic benefits that arise from its ability to activate AMP-activated protein kinase (AMPK), a critical regulator of cellular energy metabolism.”

“Alterations in magnesium and oxidative status during chronic emotional stress - Young adults undergoing persistent or intermittent stress like anticipating military conflict) experienced substantial decreases in their overall and plasma magnesium concentrations over three months.”

“While typical muscle-oriented creatine supplementation protocols (3–5 grams daily) can benefit bone indirectly through increased muscle mass, emerging evidence suggests that higher doses (up to ~8–10 grams/day) might be optimal for maximizing creatine's potential bone benefits in aging populations, especially when paired with weight-bearing exercise.”

“00:44:53 - How marine omega-3 fatty acids EPA and DHA may be one of the safest supplements to delay telomere attrition, with each 1-standard deviation increase in levels associated with a 32% reduction in the odds of telomere shortening and how one four-month double-blinded supplementation study showed that omega-3 could even lengthen telomeres.”

“- Dr. Mark Mattson https://www.foundmyfitness.com/episodes/mark-mattson/'] Whether we induce energetic crises through fasting, exercising, or tapping into a subset of the body's metabolic program through a specialized diet, some of the more compelling entities that define the ensuing metabolic switch are ketone bodies.”

“People who have narcolepsy, a chronic neurological disorder, experience very irregular sleep-wake cycles and may fall asleep during routine daily activities such as driving or troubleshooting a difficult problem.”