Search results for neurodegeneration

“Animal studies showed the bacteria play a role in more rapid disease progression and blocking the bacteria from entering the brain slowed the neurodegeneration. In a podcast I recorded with Dr. Dale Bredesen he discussed the role of the bacteria P.”

“Interestingly, findings from animal studies suggest that this cycle can be reversed by increasing butyrate-producing bacteria in the gut – another indication of the ties between the gut and overall health. ##LPS compromises the blood-brain barrier, leading to neurodegeneration.”

“Previous research has shown that the SARS-CoV-2 spike protein binds to heparin (a protein involved in blood clotting) and heparin binding proteins, accelerating the aggregation of proteins involved in neurodegeneration.”

“Judith Campisi, PhD, is a professor of biogerontology at the Buck Institute for Research on Aging. She is an expert in understanding why age is the greatest risk factor for developing a wide array of diseases, from neurodegeneration to cancer.”

“Those with low testosterone and high neurofilament light chain levels were approximately six times more likely to experience cognitive decline. These findings suggest that lower testosterone and neurodegeneration synergistically contribute to cognitive decline in men.”

“Degeneration of brain capillary pericytes leads to neurodegeneration and leaks in the blood-brain barrier "If the pericytes are not there; you can easily assume that your blood flow will be disturbed.”

“Suppression of oxidative stress by β-hydroxybutyrate, an endogenous histone deacetylase inhibitor. Long-term calorie restriction in humans is not associated with indices of delayed immunologic aging: A descriptive study. NAD+ in aging, metabolism, and neurodegeneration.”

“Surprisingly, high levels of the inactive form of B12 correlated with increased tau protein, a marker of neurodegeneration. These findings suggest that current B12 guidelines don't fully capture what the brain needs to function correctly and that even "normal" B12 levels could contribute to neurological changes.”

“Taken together, the findings suggest that lower oxygen availability may slow neuronal damage and reverse some Parkinson’s symptoms, even after they emerge. More importantly, they implicate tissue hyperoxia and oxidative stress as modifiable drivers of neurodegeneration in this model.”

“Type 2 diabetes and obesity increase a person's risk of developing dementia and other forms of neurodegeneration, particularly when the two conditions occur together. However, newer antidiabetes drugs may mitigate this risk.”