Search results for oxidative stress

“In this FoundMyFitness Journal Club clip, Dr. Rhonda Patrick and Brady Holmer explain how faster blood flow creates shear stress along the endothelium, stimulating nitric oxide signaling, vasodilation, and vascular adaptation.”

“Sustained higher exposure can also increase oxidative stress, inflammation, and fibrosis in the liver. Alcohol-associated liver disease and metabolic dysfunction-associated steatotic liver disease are distinct conditions, although they can overlap.”

“Sulforaphane activates Nrf2, a master regulatory gene that orchestrates the expression of protective proteins that aid the body in combating oxidative stress. In this clip, Dr. Rhonda Patrick discusses the many ways in which sulforaphane aids the body in excreting harmful compounds.”

“Nrf2 regulates the expression of cytoprotective proteins that protect against oxidative stress due to injury and inflammation. Sulforaphane is the most potent naturally occurring inducer of Nrf2.”

“Candidates include vitamin D, omega-3 fatty acids, and TA-65, a product that purportedly contains extracts of astragalus membranaceus, a plant-based compound that demonstrates immunomodulatory, anti-oxidative stress, and anti-aging effects, the latter of which are associated with longer telomeres.”

“Glutathione helps prevent damage from oxidative stress caused by the production of reactive oxygen species that can occur after a traumatic brain injury. In this clip, Dr. Dominic D'Agostino discusses the neuroprotective potential associated with a combination of ketones and lactate in the management of traumatic brain injury.”

“Repeated breathing interruptions fragment sleep and create cycles of falling and recovering oxygen levels throughout the night. Intermittent hypoxia and sleep fragmentation can increase oxidative stress, inflammation, and cognitive strain.”

“Disturbances in this system may heighten oxidative stress contributing to worse COVID-19 outcomes. In this clip, Dr. Roger Seheult and Dr. Rhonda Patrick discuss how vitamin D levels might affect the renin-angiotensin-system and how this relates to COVID-19 outcomes.”

“Mitochondria rely on several compounds to transport fuel, transfer electrons, and manage oxidative stress. Dr. Rhonda Patrick reviews L-carnitine, CoQ10, alpha-lipoic acid, and PQQ, explaining how their biochemical roles connect to interest in supplementation.”

“A placebo-controlled trial in people with type 2 diabetes already using glucose-lowering drugs found improvements in glycemic and selected oxidative-stress measures with black cumin supplementation. The practical context is an adjunct to established care, diet, and exercise.”