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“Visceral fat can respond to changes in energy balance and physical activity. A meta-analysis of 40 randomized trials and 2,190 adults with overweight or obesity found that both exercise and calorie restriction reduced CT- or MRI-measured visceral fat.”

“A prolonged fast has additional benefits compared to an overnight fast. Overnight the body still has liver glycogen and is not forced to begin burning fat. However, after two days of fasting, or a fasting-mimicking diet, the body starts to burn visceral fat as energy.”

“The modeled relationship between vigorous and moderate activity varied by outcome: one vigorous minute corresponded statistically to 4.1 moderate minutes for all-cause mortality, 7.8 for cardiovascular mortality, 3.5 for mortality from selected activity-related cancers, and 1.6 for cancer incidence.”

“However, the DNAm GrimAge epigenetic clock is a highly reliable predictor of healthspan and lifespan, based on DNAm surrogates in blood, including biomarkers of aging and alterations in blood composition.”

“DNA-methylation clocks use patterns in blood or other tissues to estimate aspects of biological aging. In this clip from Dr. Rhonda Patrick's presentation at Natural Products Expo West, she discusses how omega-3 fatty acids may influence these research biomarkers.”

“A meta-analysis of 25 prospective studies associated each additional 10 grams of daily fiber with about a 10 percent lower risk of colorectal cancer, with especially consistent findings for cereal fiber and whole grains.”

“Inflammatory markers, such as cytokines, are elevated in people with depression. Investigators observed that a subset of patients treated for hepatitis C using repeated doses of interferon-alpha, which stimulates inflammation, developed depression.”

“According to the Controlled Substances Act, they have a high potential for abuse, no currently accepted medical use in treatment in the United States, and a lack of accepted safety for use of the drug or other substance under medical supervision.”

“In a randomized factorial design, participants were assigned to one gram per day of algae-derived omega-3 or placebo, 2,000 IU of vitamin D3 or placebo, and a 30-minute home strength program three times weekly or a flexibility control.”

“Physical activity, sleep, light exposure, heat, and certain nutrients may all affect systems involved in mood regulation, including inflammation, circadian rhythms, neuroplasticity, and brain energy metabolism. In this Aliquot, Drs.”