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“A 2023 network meta-analysis of 270 randomized trials found average reductions after aerobic, dynamic resistance, combined, high-intensity interval, and isometric training, with the largest pooled estimate for isometric exercise.”

Dr. Rhonda Patrick explores creatine, dairy's effect on polyphenols, eggs' health impact, and new weight loss drugs like Ozempic in her latest Q&A.

Dr. Rhonda Patrick discusses GLP-1 agonists, alpha-lipoic acid, ubiquinone vs. ubiquinol, calcium needs, and liquid biopsy cancer screening.

“Genetic predisposition, altered glucose uptake in the brain, high blood pressure, and other factors can weaken the barrier's integrity, allowing endotoxins and inflammatory immune cells to infiltrate the brain and increasing a person's risk for dementia.”

“After reading about an endurance race called Ultraman, he decided to enter. Since becoming a vegan, Rich has been a repeated top finisher in the Ultraman World Championships in Hawaii, which is a three-day, 515-kilometer (320-mile) annual endurance race held on the Big Island of Hawaii.”

“Acute activation of the immune system (from exercise or sauna use for example) can temporarily reduce inflammation and the depression that can come with it. The segments brought to you by this episode of The Aliquot feature professor of psychiatry Dr. Charles Raison.”

“Across the modeled dose-response curves, one vigorous minute corresponded to 4.1 moderate minutes for all-cause mortality, 7.8 for cardiovascular mortality, 5.4 for major cardiovascular events, 9.4 for incident type 2 diabetes, and 3.5 for cancer mortality.”

“Another randomized study found better long-term picture-location memory when exercise occurred four hours after learning, showing that timing can shape the result. Dr. Patrick also discusses serotonin and hippocampal neurogenesis as a possible biological link.”

“In more than 25,000 adults who reported no leisure-time exercise, a median of three one- or two-minute bouts per day was associated with 38 to 40 percent lower all-cause and cancer mortality and 48 to 49 percent lower cardiovascular mortality compared with no VILPA.”

“While it’s likely that there may be more going on with depression than just inflammation by itself, it could be an incredibly useful lens through which to look at promising avenues to potentially treat or prevent it, since controlling systemic inflammation shows promise as being both important for longevity and health in general.”