Search results for stem cells

“The study authors increased the expression of Cdk4/cyclinD1, a multi-protein complex that governs the cell cycle and its progression, in neural stem and progenitor cells (NSC) to enhance both their cell cycle activity and proliferation in mice.”

“The algae extract was able to keep 90% of the stem cells alive for 3 days at room temperature (which is not usually possible).”

“The second person with HIV that received a stem cell transplant that replaced their white blood cells with HIV-resistant versions appears to be free of the HIV virus after treatment. The research is too early to say whether they have been completely cured of the virus but so far seems promising.”

“In recent decades, scientist Shinya Yamanaka identified a group of proteins that can reprogram differentiated (mature) cells into pluripotent stem cells. These five proteins, now named Yamanaka factors, are highly expressed in embryonic stem cells in mice and humans.”

“The stem cells decreased the innate immune response to injury which helped preserve the blood-brain barrier and improve long-term outcomes by lowering microglial cell activation that occurs in response to the brain injury.”

“When they treated human cervical cancer stem cells with phenethyl isothiocyanate (PEITC) in a Petri dish, about 75 percent died within 24 hours using a 20-micromolar concentration of the compound.”

“DNAm age was near zero in embryonic and induced pluripotent stem cells, increased with cell passage number, and worked across a broad range of tissues. In cancer, all 20 cancer types analyzed showed substantial age acceleration, averaging about 36 years.”

“Dr. Shinya Yamanaka discovered a group of proteins that can reprogram differentiated (mature) cells into pluripotent stem cells. These proteins, now called Yamanaka factors, are highly expressed in embryonic stem cells in mice and humans.”

“Proteins called Yamanaka factors can reprogram differentiated (mature) cells into pluripotent stem cells. However, scientists don’t fully understand the metabolic requirements underlying this process.”

“Scientists are exploring a wide range of cutting-edge therapies aimed at understanding and manipulating the complex processes underlying these hallmarks, including epigenetic aging clocks and pluripotent stem cells.”