Cold exposure
“Pharmacological depletion of norepinephrine can lead to depression. Clinicians sometimes treat ADHD and depression with norepinephrine reuptake inhibitors, but these drugs carry some risks.”
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“Pharmacological depletion of norepinephrine can lead to depression. Clinicians sometimes treat ADHD and depression with norepinephrine reuptake inhibitors, but these drugs carry some risks.”
“Randomized double-blind placebo-controlled trial finds 68% of patients using bright white light therapy achieved remission of depression compared to 22% of patients who received the placebo light.”
“A new study suggests that seasonal variation in the Nrf2 antioxidant pathway regulates winter depression-like behavior in fish. Nrf2 (short for nuclear factor erythroid 2-related factor 2) is a cellular protein that regulates the expression of antioxidant and stress response proteins.”
“A new study suggests that yoga decreases symptoms of depression by increasing brain levels of gamma-aminobutyric acid. Depression is a mood disorder characterized by profound sadness, altered sleep patterns, and feelings of guilt or low self-worth.”
“The analysis revealed that anti-inflammatory treatments were more effective than placebos in reducing depression symptoms among older adults. On average, people receiving these treatments exhibited a moderate improvement in symptom severity compared to those taking a placebo.”
“The risk of major depression has been shown to increase by 44% for each standard deviation increase in log c-reactive protein (inflammatory biomarker). Inflammation is caused by a variety of factors including emotional/social stress, poor diet, sedentary lifestyle, poor sleep, and more.”
“Side effects of the drugs include nausea, weight gain, decreased libido, and anxiety, among others. Evidence suggests that antidepressants are only about 20 to 30 percent more effective at reducing symptoms of depression than placebo treatments.”
“When it comes to brain health, dietary choline is associated with lower risks for cognitive impairment, post-stroke depression, and dementia. Early childhood choline intake appears to be especially important for neurodevelopment, memory, attention, and learning.”
“LPS plays a role again, as even low-dose exposure to the endotoxin can drive inflammaging, increasing inflammatory markers as much as a hundredfold. Brain function and mood disorders Compelling evidence suggests that the relationship between inflammation and depression is causal, and LPS may play a role.”
“Several non-pharmacological adjunct therapies have demonstrated effectiveness in modulating the symptoms of depression, including exercise, dietary modification, meditation, sauna use, and light therapy. Learn more about these approaches in our overview article on depression.”
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