Search results for mitochondria

“Urolithin A also improved the function of lysosomes, cellular structures that play a crucial role in mitophagy, by breaking down and recycling damaged mitochondria. These findings suggest that urolithin A boosts mitophagy in mice, improving brain health and cognitive function.”

“A new study shows a saturated fatty acid called stearic acid improved mitochondrial structure and function after oral ingestion in both healthy and diabetic people. There was also an increase in the utilization of stearic acid by the mitochondria.”

“They also showed that the two substances rescued the toxic effects of the weed killer Paraquat. Cells that had been treated with this herbicide, which is known to cause a Parkinson's like harm of mitochondria, recovered after the addition of the two substances.”

“Several studies show that HIIT improves glucose metabolism, increases mitochondrial biogenesis (the growth of new mitochondria), mitochondrial function, β-oxidation (the use of fatty acids for energy), and also the levels of glucose transporters in muscle cells all of which improve insulin sensitivity.”

“Only the BFRT group showed clear improvements in skeletal muscle mitochondrial respiration, which reflects how effectively mitochondria generate cellular energy (ATP). The activity of citrate synthase, an enzyme used as a marker of mitochondrial content, also increased only in this group.”

“One potential compound in mushrooms that may have brain benefits is ergothioneine. It is a unique antioxidant and anti-inflammatory compound that also accumulates in mitochondria. Humans are unable to synthesize ergothioneine on their own but it is present in a variety of mushrooms.”

“Researchers collected several small muscle samples from the thigh to measure pyruvate dehydrogenase activity (PDH, an enzyme complex that helps muscles convert carbohydrate fuel into energy inside mitochondria), along with changes in gene expression and protein levels related to oxidative phosphorylation (OXPHOS, the main process mitochondria use to produce energy).”

“They found that at the end of the six-week exercise program, the women who were diet resistant exhibited improved body composition and muscle metabolism and increased numbers of muscle mitochondria. The exercise program elicited only minimal effects in women who were diet sensitive.”