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“While daily fluctuations in testosterone do not drive muscle protein synthesis, supraphysiological steroid doses are anabolic. Testosterone boosters come and go, but Dr. Phillips states they are ineffective, and it's better to focus on resistance exercise.”

“Generally, they lack ordinary exposure to diseases and accidents that can promote sudden stretches of disuse and consequent atrophy of muscles. Without adequate muscle reserve built when young and preserved when old, we more quickly reach a "disability threshold."”

“These findings suggest that drop sets are a time-efficient resistance-training strategy for promoting muscle growth. Some of the mechanisms that promote muscle hypertrophy with resistance training include mechanical tension and metabolic stress.”

“Creatine helps supply energy to muscles during high-intensity exercise and is commonly used to boost performance and muscle mass. However, determining the most effective creatine supplementation protocol has proven challenging.”

“The overall result, a loss of visceral fat without depleting lean muscle mass, is a desirable feature of a prolonged fast, particularly for athletic performance. In this clip, Dr. Valter Longo describes how a fasting-mimicking diet can be used for fat loss while preserving lean muscle mass.”

“McGlory and Patrick also touch upon the sex differences in muscle gains and the possible influence of estrogen on the conversion of omega-3 fatty acids. In this clip, Dr. McGlory discusses the intriguing interplay between resistance training, nutrition, and muscle adaptation, especially among older adults.”

“These benefits may be particularly important for older adults who are susceptible to muscle wasting during periods of inactivity or immobilization. In this clip, Dr. McGlory discusses the potential of omega-3 fatty acids to protect against muscle loss during periods of immobilization or inactivity.”

“Dr. Phillips submits that while these findings are exciting, more research is needed. In this clip, Dr. Stuart Phillips describes how omega-3 fatty acids may contribute to slow age-related declines in muscle mass and strength.”

“And although testosterone and other steroid hormones do influence muscle growth, they play less of a role than one might think – and may carry some risks. In this second part of our two-part Aliquot, Dr. Stuart Phillips and I continue our discussion on the role that nutrients and supplements play in muscle adaptation.”

“In this clip from Dr. Rhonda Patrick's appearance on the Jack Neel Podcast, she extends the energy discussion from muscle to the brain. Brain creatine responds less predictably to supplementation, and the clearest early cognitive signals appear when energy demand is high.”