FoundMyFitness library
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“When we engage in high-intensity exercise, our muscles become mini biochemical laboratories, synthesizing compounds like lactate and myokines that circulate throughout the body and travel to our organs, where they exert a variety of signaling effects, including the synthesis of brain-derived neurotrophic factor (BDNF) in the brain.”
“Practical ways to use short bouts Choose the version that matches the goal rather than forcing every short activity into one label: For a vigorous fitness stimulus Select a familiar movement such as stairs, a stationary bike, uphill walking, or a bodyweight circuit.”
“Unlike chemicals that are rapidly eliminated in urine, some long-chain PFAS undergo biliary excretion and intestinal reabsorption, contributing to biological half-lives measured in years and the nickname “forever chemicals.” PFAS exposure may increase the risk of cancer, liver damage, and immune system impairment.”
“Just one month after their heart attack, participants assigned to 16:8 time-restricted eating experienced a 6.6% increase in a measure of their heart’s pumping efficiency known as left ventricular ejection fraction (LVEF) compared to a mere 1.5% increase in the regular diet group.”
“For example, a large, population-based study that drew data from more than 170,000 men and women between the ages of 30 and 75 years showed that animal protein intake was associated with increased death rates only when the participants had at least one unhealthy lifestyle risk factor such as smoking, heavy alcohol consumption, physical inactivity, or being overweight or obese.”
“In a study involving diet-induced diabetic mice, injection of 500 milligrams per kilogram of body weight (mg/kg/bw) of nicotinamide mononucleotide administered for seven days enhanced insulin sensitivity and improved glucose intolerance compared to that observed among mice not given nicotinamide mononucleotide.”
“Obesity In a study in which mice were fed a diet that was high in fat and sugar and received a 400-milligram per kilogram of body weight (mg/kg/bw) nicotinamide riboside supplement every day for one week, the mice gained 60 percent less fat, exhibited improved insulin sensitivity, and demonstrated greater endurance and muscle strength, compared to mice that did not receive the supplement.”
“A series of meta-analyses involving 925 participants across 15 randomized placebo-controlled clinical trials explored the anti-inflammatory effect of quercetin supplementation in both healthy adults and people who had been diagnosed with a disease, including type 2 diabetes, metabolic syndrome, coronary artery disease, rheumatoid arthritis, and obesity.”
“Another study in which 22 year old men who engaged in four weeks of high-intensity interval training three days a week and supplemented with 150 milligrams of resveratrol per day, the lowest dose of the studies mentioned so far, did not promote increases in the men's aerobic or anaerobic capacity, exercise substrate utilization, or muscle fiber-specific adaptations compared to exercise alone.”
“Taking it a step further, they investigated how sodium and potassium impact blood pressure in men and women differently—a critical question since cardiovascular diseases disproportionately affect men compared to women due to differences in nitric oxide bioavailability, inflammation, electrolyte balance, and sympathetic nervous system activity.”