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“Interestingly, repeated exposure to whole-body heat treatment through sauna use has an even more profound effect on boosting growth hormone immediately afterward: Seventeen men and women who were exposed to two one-hour sauna sessions at 80°C (176°F) dry heat (typical Finnish-style sauna) per day for seven days exhibited a 16-fold increase in growth hormone levels by the third day.”
“In addition, a randomized, placebo-controlled, double-blind trial involving people diagnosed with mild-to-moderate dementia due to Alzheimer's disease found that participants who took a resveratrol supplement twice a day (up to 1 gram) for one year exhibited reduced levels of MMP9, a neurological inflammatory marker associated with increased neurodegeneration and inflammation.”
Small vessel disease is a generic term that describes dysfunction of blood vessels that occurs with aging and contributes to cognitive decline, cardiovascular disease, frailty, and stroke.
“After taking into account other factors, including age, race/ethnicity, poverty/income, tobacco and alcohol consumption, and physical activity, the authors also found that participants with overweight and obesity were nearly four times more likely to have low serum testosterone compared to lean males, independent of SSB consumption.”
Toll-like receptors are a family of pattern recognition receptors expressed on the surface of immune and other cells that play an important role in intestinal permeability and inflammaging.
“UPFs cause metabolic and cognitive changes in less than a week "...just 5 days of a high-calorie diet made the brains of these healthy, normal weight men structurally and functionally similar to people with obesity, and even after cutting the high-calorie foods out of their diet, these changes persisted for at least one week."”
Intravenous Vitamin C for the treatment of sepsis Sepsis, a life-threatening condition that can arise due to the body's response to a bacterial or viral infection, can cause severe injury to multiple tissues or organs.(Source: CDC) (https://www.cdc.gov/sepsis/index.html) People diagnosed with sepsis typically have low vitamin C levels, which might be predictive of increased risk for organ failure.
“The active whole body hyperthermia group underwent mild-intensity hyperthermia using a Heckel device, with infrared lights heating the chest and coils warming the lower extremities until their core temperature reached 38.5°C—a process taking an average of 107 minutes (range 81–140 minutes)—followed by a 60-minute cool-down phase.”