Related Episodes for Anti-cancer effects of ketones | Dominic D'Agostino

Dan Pardi: Ph.D. candidate studying sleep neurobiology at Stanford and University of Leiden, co-founder of Dan’s Plan online wellness company.

“Dr. Candow explains why a hormone change within the physiological range cannot by itself establish a hair effect. A later 12-week randomized trial directly measured hormones and hair-follicle outcomes in resistance-trained men taking five grams of creatine per day.”

“Tools, companies, and resources mentioned OpenAI - AI research and deployment company behind widely used GPT systems and developer tools; its science case study describes GPT-5 helping Unutmaz's lab resolve a long-standing immunology question.”

“Moreover, taking mega doses (i.e. 400 IU/day) of alpha tocopherol has the unintended side-effect of actually depleting tissue levels of another important form of vitamin E that plays an anti-inflammatory role, known as gamma tocopherol.”

“Aging in tumor tissue is markedly accelerated, however – an indicator of the perturbed metabolic and growth processes observed in cancer. In this clip, Dr. Steve Horvath discusses correlations between epigenetic aging and age-related chronic diseases.”

“Patients assigned to supervised exercise during neoadjuvant chemoradiation, followed by continued activity before surgery, were more likely to achieve a complete or near-complete pathological response than those receiving usual care.”

“Dr. Patrick describes increased shear as a possible way vigorous exercise can damage fragile circulating tumor cells; this is a proposed mechanism, not proof that a workout eliminates metastasis or treats an established tumor.”

“In 25,241 adults who reported no structured exercise, a median of three one- or two-minute vigorous lifestyle bouts per day was associated with 38% to 40% lower all-cause and cancer mortality and 48% to 49% lower cardiovascular mortality.”

“Dr. Patrick also describes a proposed anti-metastatic mechanism: faster blood flow during vigorous exercise increases shear forces on circulating tumor cells, the cells that have left a primary tumor and entered the bloodstream.”

“In this excerpt from Dr. Rhonda Patrick’s A4M LongevityFest 2023 keynote, she reviews a randomized trial in sedentary middle-aged adults. Two years of progressive, supervised aerobic training increased VO2 max and reduced left-ventricular stiffness.”