Related Episodes for Can caloric restriction supplements mimic fasting? | Dr. Mark Mattson

“In this FoundMyFitness Premium Q&A preview, Dr. Rhonda Patrick reviews common contributors to fragmented sleep, including insomnia, sleep apnea, nocturia, psychological stress, irregular schedules, caffeine, alcohol, light, noise, temperature, and late eating.”

“Dr. van Loon sees useful research questions in skin, joints, and recovery after orthopedic surgery, but he keeps those possibilities separate from established muscle-building effects.”

“New Scientist article. 02:06:10 - Some people, like Tom Cruise and Keanu Reeves, seem to defy aging. 02:08:15 - One 12-ounce can of sugar-sweetened soft drink per day shortened telomere length, corresponding to 4.6 years of biological aging.”

“Dr. Patrick recommends bounded quality checks such as GMP manufacturing and independent testing; she notes that some tested products were below their stated heavy-metal limits, not that lion’s mane products are uniformly contaminated.”

“A higher omega-3-index quintile was associated with lower all-cause mortality risk, but the estimated years of life were model-derived comparisons between quintiles, not observed gains from raising an index from 4% to 8%.”

“A later Framingham analysis followed 2,240 adults for 11 years and found that a red-cell fatty acid model including the Omega-3 Index predicted all-cause mortality about as well as a model using several standard cardiovascular risk factors.”

“In addition it can be hard to keep track of the nutrient content of the food one eats. For these reasons, Bruce says that taking a “multivitamin and mineral is a good insurance.” However he also qualifies the statement by saying that too much vitamins or minerals can be a bad thing too.”

“More than a century of research has demonstrated that nicotinamide adenine dinucleotide (NAD+) is an indispensable mediator of vital metabolic and physiological processes, including energy production, DNA synthesis and repair, and regulation of gene expression – across multiple species.”

“A randomized-trial meta-analysis found a higher atrial-fibrillation risk with marine omega-3 supplementation, with a stronger signal at doses above 1 gram per day; the included populations generally had cardiovascular disease or elevated cardiovascular risk.”

“Dr. Bill Harris shares his nuanced insights into whether omega-3 supplementation carries a bleeding risk. Dr. Harris bases his understandings on observations from clinical trials using extreme dosages, additional research that directly contradicts omega-3 intake as a generalized concern for bleeding risk during surgery, as well as comments from the FDA.”