Related Episodes for How Coffee Timing Relates to Longevity

“A meta-analysis of resistance-training trials found that protein supplementation produced modest additional gains in strength and fat-free mass, with average fat-free-mass benefit plateauing near 1.62 g/kg/day. This is a group estimate, not a precise requirement for every older adult.”

“In a small immobilization trial, five grams per day of omega-3 fatty acids reduced the loss of muscle volume in young women compared with sunflower oil, supporting continued research on omega-3s and disuse atrophy. Heat is the fourth proposed tool.”

“The question of whether NAD+ is derived directly from NR or NMN in certain tissues rather than being salvaged from nicotinamide may, in particular, have implications for whether or not oral administration may be hampered in achieving maximal NAD+ status due to the fact that the process of salvaging NAD+ from nicotinamide is subject to feedback inhibition.”

“Dr. Patrick therefore favors lower-risk tools for focus, including high-quality sleep, exercise, cocoa flavanols, deliberate cold exposure, and modest caffeine, before considering an addictive stimulant. Nicotine is not equivalent to tobacco smoke, but that does not make chronic use benign.”

“A randomized-trial meta-analysis found a higher atrial-fibrillation risk with marine omega-3 supplementation, with a stronger signal at doses above 1 gram per day; the included populations generally had cardiovascular disease or elevated cardiovascular risk.”

“EPA and DHA play particularly important roles in heart health because they participate in pathways involved in the production of hormones that regulate blood clotting and inflammation, help maintain healthy heart rhythms, and influence the contraction and relaxation of arteries.”

“It remains unknown whether these levels are sufficient for optimal immunological functioning. A large meta-analysis of 32 studies, spanning nearly 50 years, suggests that 25-hydroxyvitamin D levels below 30 ng/mL are associated with a higher risk of death from all causes.”

“Dr. Bruce Ames' Triage Theory Dr. Ames proposed that the body does a strategic rationing so that those proteins and enzymes in the body which are essential for short-term survival get their share of vitamins and minerals at the expense of other proteins and enzymes that are essential for long-term survival.”

“Dr. Patrick also discusses STEP 5, in which two years of treatment produced about 15.2 percent loss versus 2.6 percent with placebo, with the curve leveling while participants remained on treatment. Dual GIP/GLP-1 therapy can produce still larger losses in some trials.”

“In this clip from his FoundMyFitness interview with Dr. Rhonda Patrick, Dr. Luc van Loon explains that protein requirements adapt to habitual high or low intake, but the size and clinical meaning of that adaptation remain uncertain.”