Ranked by shared topics, with one result from each original episode.
“It suggests that when the body runs low on essential vitamins or minerals, it doesn't distribute them evenly. Instead, it prioritizes urgent survival tasks, like keeping the heart beating or clotting blood, over long-term maintenance, such as repairing DNA or defending against oxidative damage.”
“In this Aliquot, I'll explore how to recognize and address iron deficiency, the unique challenges of iron overload in aging, the ways alcohol may influence brain iron, and how infants tightly regulate iron as a built-in defense against infection.”
“From THC, CBD, alcohol, caffeine, and nicotine to melatonin, magnesium, glycine, and calming botanicals, these compounds can either support restorative sleep or subtly hijack it, changing REM, deep sleep, and circadian timing in ways we often do not feel until the next day.”
“In this Aliquot, along with Dr. Eran Elinav, I explore how gluten affects the gut barrier, who actually needs to avoid it, and the practical strategies that can help you build a more resilient gut.”
“In this Aliquot, I'm joined by exercise-oncology researcher Dr. Kerry Courneya to identify and prioritize the lifestyle behaviors that account for much of the difference in cancer risk and have the greatest long-term impact.”
“In this Aliquot, I walk through how that plays out in humans, where the strongest evidence shows up, and where it doesn't, with NAD researcher Dr. Charles Brenner—and why I'm taking it now after being skeptical.”
“Modulating autophagy – through fasting and exercise (which both increase acetyl CoA) or intake of nutrients like spermidine – represents a promising therapeutic approach for extending human lifespan and healthspan.”
“It has attracted interest for its potential to activate mitophagy, the process cells use to clear out damaged mitochondria. In this Aliquot, I explain why mitochondrial cleanup matters for aging, why urolithin A production varies, and what early human studies suggest about its potential benefits.”
“Because some long-chain PFAS travel through a similar pathway, researchers are now asking whether beta-glucans might also help the body eliminate these persistent "forever chemicals."”
“Insulin-like growth factor-1, or IGF-1 for short, is a protein that plays critical roles in major growth pathways in the human body. It influences nearly every tissue in the body, especially developmental growth, skeletal muscle and neurons.”