Ranked by shared topics, with one result from each original episode.
“From THC, CBD, alcohol, caffeine, and nicotine to melatonin, magnesium, glycine, and calming botanicals, these compounds can either support restorative sleep or subtly hijack it, changing REM, deep sleep, and circadian timing in ways we often do not feel until the next day.”
“In this Aliquot, sleep scientist Dr. Michael Grandner explains why sleep apnea is so often missed, how these nightly breathing disturbances affect the body, and which treatments can meaningfully improve sleep and long-term health.”
“The different stages of sleep provide crucial periods during which the body recalibrates to promote both mental and physical well-being. In this clip, Dr. Matthew Walker describes how the different stages of sleep influence emotional and cardiovascular health.”
“Shift work creates a chronic disruption of circadian rhythms that affects sleep, metabolism, decision-making, and long-term health, often in ways people don't recognize until years later. In this Aliquot, joined by Drs.”
“These changes increase infection risk, weaken vaccine responses, and reduce early cancer surveillance. Yet immune aging is not fixed. Movement, sleep, stress regulation, temperature exposure, and nutrition shape immune cell balance and inflammatory activity over time.”
“In this Aliquot, Drs. Satchin Panda, Andrew Huberman, Layne Norton, Brad Schoenfeld, Martin Gibala, and I examine how circadian biology, training intensity, and life schedule shape exercise timing. We also explore what that means for deciding when to train.”
“In this Aliquot, I explain why visceral fat behaves so differently from other fat, how it drives insulin resistance and chronic disease, and what research shows about the most effective ways to reduce it.”
“In this Aliquot, I walk through how that plays out in humans, where the strongest evidence shows up, and where it doesn't, with NAD researcher Dr. Charles Brenner—and why I'm taking it now after being skeptical.”
“Physical activity, sleep, light exposure, heat, and certain nutrients may all affect systems involved in mood regulation, including inflammation, circadian rhythms, neuroplasticity, and brain energy metabolism. In this Aliquot, Drs.”
“It has attracted interest for its potential to activate mitophagy, the process cells use to clear out damaged mitochondria. In this Aliquot, I explain why mitochondrial cleanup matters for aging, why urolithin A production varies, and what early human studies suggest about its potential benefits.”