Related Episodes for Dr. Dale Bredesen on Preventing and Reversing Alzheimer's Disease

“Researchers have determined that beta-hydroxybutyrate is an endogenous regulator of HDACs and is able to regulate age-related genes such as FOXO3. In this clip, Dr. Eric Verdin discusses the role of beta-hydroxybutyrate in protecting against oxidative stress, both as a nutrient, but also as a transcription regulator.”

“For instance, while the U.S. has high obesity rates, its rates of type 2 diabetes remain modest compared to countries like Singapore, India, and many Middle Eastern nations—populations that, on average, tend to have "fatter fat cells" and therefore develop metabolic complications at lower body mass indices (BMIs).”

“Breast milk contains a diverse and highly complex community of microbes that come from a variety of sources. Exposure to this community may contribute to the differences observed in gut microbial populations between breastfed and formula-fed infants. In this clip, Dr. Rhonda Patrick describes the unique community of microbes present in human breast milk.”

“Premenopausal females have much lower rates of cardiovascular disease than similarly aged males because of the protective effects of estrogen, but after menopause, there's not much of a difference, and cardiometabolic risk factors actually worsen in females during the menopause transition, indicating this may be a crucial time for exercise intervention to protect the cardiovascular system.”

“Dr. Patrick treats magnesium L-threonate separately. Early human findings are limited by small studies, industry funding, and products that sometimes include coingredients, making it difficult to attribute effects to L-threonate alone.”

“An enriched marine-oil study produced time- and dose-dependent increases in specialized pro-resolving mediators and altered blood-cell responses over 24 hours; it tested biomarkers, not disease prevention. Exercise, sauna, and cruciferous vegetables act through different pathways.”

“In this video, Dr. Darya & Kevin Rose talk about beta-hydroxybutyrate, an endogenous ketone body that increases in concentration during times of fasting or carbohydrate restriction. Beta-hydroxybutyrate also increases during a fasting-mimicking diet, which is a time of temporary period of calorie and protein restriction that generates many of the same biochemical effects of prolonged fasting.”

“A common feature of heart disease is arrhythmia, an irregular heartbeat. Interestingly, research in fruit flies has shown that unhealthy lifestyle behaviors, such as poor sleep and diet, increase the risk of developing arrhythmias.”

“Unique qualities of the marine omega-3 fatty acids EPA and DHA There are several omega-3 fatty acids, but the ones that have the greatest relevance for human health are the two identified in the Inuit's blood – EPA and DHA – as well as alpha-linolenic acid (ALA), which is found in a wide variety of seeds, nuts, and their oils.”

“- Practical details like temperature and duration of sauna use, the difference between a dry, wet and infrared sauna, sauna timing, as well as other forms of heat stress such as steam showers, hot baths, and hot yoga.”