Related Episodes for Deprivation of nutrients (starvation) and other signals that play a key role in inducing autophagy

“In this video, Dr. Darya & Kevin Rose talk about beta-hydroxybutyrate, an endogenous ketone body that increases in concentration during times of fasting or carbohydrate restriction. Beta-hydroxybutyrate also increases during a fasting-mimicking diet, which is a time of temporary period of calorie and protein restriction that generates many of the same biochemical effects of prolonged fasting.”

“Research has identified a few biohacks – lifestyle strategies that improve health and lifespan – that may extend telomeres. The goal of these strategies, which include mindfulness, yoga, exercise, and meditation, is to reduce psychological stress and provide the mind and body periods of restoration and healing.”

“He observed that in most cases, metabolic rates were a reflection of body mass and closely tracked estimations from predictive equations. In this clip, Dr. Ray Cronise emphasizes the importance of diet to improve healthspan rather than employing tricks to boost metabolic rate.”

“These transient stressors induce the expression of genes that process inflammatory molecules. In this clip, Tim Ferriss and Dr. Rhonda Patrick discuss acute versus chronic inflammation and how supplemental antioxidants can negate some of the benefits of exercise.”

“Dr. D'Agostino asserts that a low carbohydrate diet incorporating intermittent fasting probably has more benefits than chronic ketosis for most healthy adults. Drs. D'Agostino and Patrick describe their experiences with fasting or time-restricted eating and its calming effects on the brain.”

“Although some evidence suggests that black, caffeinated coffee or tea may have little effect on the beneficial effects associated with time-restricted eating, experts in the field of circadian biology suggest a more conservative approach that permits coffee and tea only during the designated window of eating.”

“Lunch varied among sardines, mackerel, wild salmon, avocado, nuts, fruit, cheese, and quinoa salad, giving her flexible sources of protein, marine fats, fiber, and fermented foods. Dinner typically paired fish, chicken, or occasional beef with vegetables or salad.”

“Dr. Patrick explains some of the early evidence that suggests the value prolonged fasting (48+ hours) may have from the standpoint of tissue rejuvenation and healthspan maintenance, as well as relevance for other more specific conditions.”

“The body has elegant mechanisms that allow it to utilize non-carbohydrate substrates to generate glucose. Gluconeogenesis is a metabolic pathway in which the liver produces glucose from non-carbohydrate substrates including glucogenic amino acids (from protein) and glycerol (from lipids).”