Ranked by shared topics, with one result from each original episode.
“Whereas fasting turns off multiple pathways associated with aging, such as mTOR, IGF-1, growth hormone, and others, eating for optimal fitness activates these important processes. This Aliquot features Drs. Guido Kroemer, Dominic D'Agostino, Valter Longo, Peter Attia, and Rhonda Patrick.”
“Circadian rhythms play key roles in metabolic health and ultimately influence body weight, performance, and susceptibility to diseases like diabetes and cancer. Aligning food intake with circadian rhythms can improve many aspects of metabolic health.”
“A healthy intestinal barrier limits the transport of pathogens and endotoxins from the gut to the bloodstream; however, increased gut permeability (known as "leaky gut") raises endotoxin levels, leading to metabolic endotoxemia.”
“The immune system has strategies for filtering these autoimmune cells out of circulation; however, this filter can malfunction due to age, genetic predisposition, disruption of the gut barrier and gut microbiota, or other environmental exposures.”
“Dietary fiber is a broad term that refers to the non-digestible components of fruits and vegetables. Gut microbes break down certain types of fiber, releasing micronutrients trapped in the fiber matrix and producing beneficial metabolic byproducts, such as short-chain fatty acids.”
“Naturally occurring forms of vitamin K include phylloquinone, known as vitamin K1, and a family of molecules called menaquinones, known as vitamin K2. In this Aliquot, Dr. Bruce Ames and I discuss the differences between (and dietary sources of) vitamins K1 and K2 and their effects on human health.”
“Building muscle mass in one's early years is essential for staving off the age-related loss of muscle mass and may promote longevity. In this Aliquot, Dr. Stuart Phillips discusses the importance of building muscle through resistance training and why starting early is important.”
“Having sufficient muscle mass markedly reduces a person's risk of dying prematurely. Although some studies suggest that eating less protein promotes longevity, those studies might not take into account the periods of disuse and disability that often occur in real life.”
“In part one of this two-part Aliquot, Dr. Stuart Phillips and I talk about the role of nutrients and supplements in promoting muscle protein synthesis and subsequent increases in muscle mass and strength.”
“Consuming sufficient protein is essential for muscle growth and maintenance. Emphasis on specific amino acids within protein, particularly the branched-chain amino acids, probably isn't necessary unless you're an elite athlete or an older adult.”