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Related Episodes for Do healthy people benefit from intermittent fasting? | Dr. Mark Mattson

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How Much Protein Maximizes Muscle Gains

Nov 6, 2025

“A meta-analysis of 49 studies involving 1,863 adults found that protein supplementation during prolonged resistance training produced additional gains in one-repetition maximum strength, fat-free mass, and muscle size compared with training alone.”

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How Nicotinamide Riboside Relates to Exercise Recovery

Feb 25, 2026

“In eight young men, seven days of 1,000 milligrams of NR per day changed selected muscle NAD metabolites but did not alter substrate use, mitochondrial respiration, or signaling involved in adaptation to one hour of endurance exercise.”

exercise aging metabolism inflammation
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How Omega-3, Vitamin D, and Exercise Affected Aging Clocks

Jun 10, 2026

“In a randomized factorial design, participants were assigned to one gram per day of algae-derived omega-3 or placebo, 2,000 IU of vitamin D3 or placebo, and a 30-minute home strength program three times weekly or a flexibility control.”

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How Omega-3s Support the Aging Brain

Sep 16, 2026

“In the prospective Framingham Offspring Study, people in the highest red-blood-cell DHA group had approximately 49 percent lower risk of developing Alzheimer's disease than those in the lowest group.”

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How to Combine Exercise With Compassion Practice

Aug 28, 2026

“A separate trial of 153 adults found that smartphone-based mindfulness training combining attention monitoring with acceptance reduced daily loneliness and increased social interactions compared with monitoring alone or an active control.”

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How Urolithin A Supports Mitochondrial Health

Aug 14, 2026

“In later randomized trials, urolithin A improved some laboratory measures of muscle endurance or hamstring strength, but it did not significantly improve key primary outcomes such as six-minute walk distance, muscle ATP production, or peak power.”

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How Vigorous Exercise Reverses Cardiac Aging

Nov 7, 2025

“A separate 46-year study of 5,107 middle-aged men linked each 1 milliliter per kilogram per minute increase in estimated VO2 max with about 45 additional days of life expectancy. High-intensity intervals are one practical way to improve VO2 max.”

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How Vigorous Interval Training Improves Heart Fitness

Sep 29, 2025

“In a randomized study of healthy adults, four four-minute intervals at 90 to 95 percent of peak heart rate performed three times weekly increased VO2 max by 7.2 percent over eight weeks and outperformed work-matched moderate training.”

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179
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Is there a limit to human longevity?

Jul 20, 2022

“There's a lot of exciting research right now into aging and maximum lifespan, but scientists have really just scratched the surface of the fascinating topic of how to live longer, healthier lives. Relevant Publications Rootzén, Holger, and Dmitrii Zholud.”

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180
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Hyperthermic Conditioning for Hypertrophy, Endurance, and Neurogenesis

Apr 10, 2014

“Dr. Rhonda Patrick discusses how conditioning the body to heat stress through sauna use, called "hyperthermic conditioning" may cause adaptations that increase athletic endurance (by increasing plasma volume and blood flow to heart and muscles) and potentially even muscle mass. She also discusses the profound effects of hyperthermic conditioning on the brain including cognitive function.”

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