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“In a small trial involving adults with obesity, a ketone monoester improved one processing-speed task and selected brain blood-flow measures, providing an early signal for further research. Temperature can also shape alertness and sleep preparation.”

“In a randomized trial of resistance-trained women, an eight-hour eating window did not reduce gains in lean mass, muscle thickness, strength, or performance when energy and protein intake were matched and the participants completed supervised resistance training.”

“Small controlled trials of early time-restricted eating, which included breakfast and moved dinner earlier rather than testing breakfast skipping, found improved insulin sensitivity in eight men with prediabetes and lower 24-hour glucose in 11 adults with overweight.”

“In a controlled five-week crossover trial involving men with prediabetes, an early six-hour eating window with dinner before 3 p.m. improved insulin sensitivity, pancreatic beta-cell responsiveness, blood pressure, oxidative stress, and appetite without causing weight loss.”