Related Episodes for History and discovery of longevity genes | David Sinclair

“Topics include hair regrowth in androgenic alopecia, pain reduction in rheumatoid arthritis with notable results but occasional study design concerns and conflicts of interest, muscle endurance, post-exercise muscle recovery, wound healing, and skin wrinkling.”

“But implementing a ketogenic diet is challenging. In this Aliquot, Dr. Dominic D'Agostino explains how to avoid side effects on a ketogenic diet, provides valuable pointers for success, and explains how the diet might help preserve muscle mass.”

“Vascular dysfunction, the loss of normal endothelial tone and permeability of blood vessels, is a common feature of most forms of dementia, including Alzheimer's disease. People who carry the APOE4 gene are at greater risk for vascular dysfunction and Alzheimer's disease.”

“In this Aliquot, Dr. Brad Schoenfeld describes a balanced approach to maximizing muscle growth and strength and dispels early myths about possible blunting effects of aerobic training, the need to train to failure, and the "go heavy or go home" philosophy.”

“However, combining fasting with resistance training can stimulate muscle growth. In this Aliquot, Dr. Rhonda Patrick discusses time-restricted eating, fasting, and muscle preservation, highlighting key differences and offering recommendations for specific groups.”

“Time-restricted eating involves consuming meals within a specific daily time window. However, choosing the optimal time frame for that window is influenced by many factors, the most important of which is circadian rhythmicity, which alters our body's metabolic responses to food.”

“While sanitation and clean drinking water are critical to survival, the over sterilization of our environment may play a role in modulating the human immune system. In this clip, Dr. Charles Raison highlights how ancient practices such as heat exposure, long-distance running, and fasting may promote well-being in the modern world.”

“Because of alcohol’s effect on other organs and the evidence that any dose of alcohol appears to elevate cancer risk, Dr. Huberman thinks that zero to two drinks per week represents a “safe zone” as long as you’re of age, not pregnant, and not an alcoholic.”

“According to the latest research on fed vs. fasted exercise: If your workout lasts longer than 60 minutes, especially aerobic (endurance-based) sessions, eating beforehand tends to improve performance Your body has quick access to glucose, which helps you go longer and harder.”

“Circadian rhythms modulate a wide array of physiological processes, including the body’s production of hormones that regulate sleep, hunger, metabolism, and others, ultimately influencing body weight, performance, and susceptibility to disease.”